Literature DB >> 27190843

Spindle Cell Carcinoma of Nasal Cavity- A Case Report.

Priyank Mistry1, Abhishek Mittal1, Tapan Nagpal2.   

Abstract

Spindle Cell Carcinoma (SpCC), also known as Sarcomatoid Carcinoma, is a rare and peculiar biphasic malignant neoplasm that occurs mainly in the upper aero-digestive tract, mostly in larynx. SCC accounts for 3% of all squamous cell carcinomas (SCCs) in the head and neck region. It is a rare variant of SCC which shows spindled or pleomorphic tumour cells simulating a true sarcoma. We present a case report of SpCC nasal cavity in a 50-year-old female patient, presented with intermittent epistaxis from left nasal cavity. On physical examination, the patient had an ulcero-exophytic type of mass in the left nasal cavity and a smooth bulge on the left side of anterior hard palate. Patient underwent excision of nasal mass along with partial palatectomy by facial degloving approach and reconstruction of palate with naso-labial flap. The postoperative histopathological report showed SCC. Surgery forms the mainstay of treatment. Radiotherapy and Chemotherapy is warranted in order to improve treatment results. As only few cases have been reported, we report a case of this rare entity to contribute for better understanding and awareness of this rare malignancy.

Entities:  

Keywords:  Facial degloving; Naso labial flap; Radiotherapy and chemotherapy; Sarcomatoid carcinoma

Year:  2016        PMID: 27190843      PMCID: PMC4866141          DOI: 10.7860/JCDR/2016/17468.7576

Source DB:  PubMed          Journal:  J Clin Diagn Res        ISSN: 0973-709X


  10 in total

1.  Spindle cell (sarcomatoid) carcinomas of the larynx: a clinicopathologic study of 187 cases.

Authors:  Lester D R Thompson; Jacqueline A Wieneke; Markku Miettinen; Dennis K Heffner
Journal:  Am J Surg Pathol       Date:  2002-02       Impact factor: 6.394

Review 2.  Pathology in focus. Spindle-cell carcinoma of the nasal septum.

Authors:  H Ahluwalia; S C Gupta; S C Gupta
Journal:  J Laryngol Otol       Date:  1996-03       Impact factor: 1.469

3.  Spindle cell carcinoma of the larynx: review of 26 cases including DNA content and immunohistochemistry.

Authors:  J E Lewis; K D Olsen; T J Sebo
Journal:  Hum Pathol       Date:  1997-06       Impact factor: 3.466

4.  Sarcomatoid (spindle cell) carcinoma of the head and neck mucosal region: a clinicopathologic review of 103 cases from a tertiary referral cancer centre.

Authors:  Seethalakshmi Viswanathan; Khaliqur Rahman; Suryawanshi Pallavi; Johari Sachin; Asawari Patil; Pankaj Chaturvedi; Anil D'Cruz; Jaiprakash Agarwal; S V Kane
Journal:  Head Neck Pathol       Date:  2010-08-22

5.  Spindle cell carcinoma of the nasal cavity.

Authors:  Tadashi Terada; Taiji Kawasaki
Journal:  Int J Clin Oncol       Date:  2010-09-14       Impact factor: 3.402

6.  Sarcomatoid carcinoma and orbital apex syndrome.

Authors:  L M Sadaba; A García-Layana; P J Garcia-Gomez; A Salinas-Alaman
Journal:  Eur J Ophthalmol       Date:  2006 Jul-Aug       Impact factor: 2.597

7.  Sarcomatoid squamous cell carcinoma of the mucous membranes of the head and neck: a clinicopathologic study of 20 cases.

Authors:  G S Leventon; H L Evans
Journal:  Cancer       Date:  1981-08-15       Impact factor: 6.860

8.  Right maxillary sinus sarcomatoid carcinoma (sarcomatoid/spindle cell carcinoma).

Authors:  Scott N Howard; William R Bond; In Soon Hong; Robert D Foss
Journal:  Otolaryngol Head Neck Surg       Date:  2007-08       Impact factor: 3.497

9.  Spindle-cell carcinoma of the aerodigestive tract. An immunohistochemical analysis of 21 cases.

Authors:  G L Ellis; J M Langloss; D K Heffner; V J Hyams
Journal:  Am J Surg Pathol       Date:  1987-05       Impact factor: 6.394

10.  Spindle cell carcinoma of the tongue: a rare tumor in an unusual location.

Authors:  Murat Oktay; Tuba Dilay Kokenek-Unal; Bulent Ocal; Guleser Saylam; Mehmet Hakan Korkmaz; Murat Alper
Journal:  Patholog Res Int       Date:  2011-02-20
  10 in total
  2 in total

1.  Spindle Cell Squamous Cell Carcinoma of the Scalp Treated With Pembrolizumab Cisplatin and 5-Fluorouracil.

Authors:  Ali M Alzahrani; Bander Al Mutari; Anas Alzahrani; Abdelhafeeth Alkhodaidi; Gaaem Yahya
Journal:  Cureus       Date:  2021-12-07

2.  Carcinosarcoma Arising from Inverted Papilloma in a Patient with History of Radiotherapy for Sinonasal Squamous Cell Carcinoma.

Authors:  Faraj Alotaiby; Mohammed N Islam; Indraneel Bhattacharyya; Donald M Cohen; Peter A Drew; Jinping Lai
Journal:  Am J Case Rep       Date:  2020-03-22
  2 in total

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