Literature DB >> 27190808

Antibiotic Adjuvant Therapy for Multi-Drug Resistant Carbapenemases Producing Klebsiella pneumoniae Associated Sepsis: A Case Study.

Robin Gupta1.   

Abstract

Rising resistance and spread of K. pneumoniae strains, create great concerns in treating sepsis patients due to high incidence of mortality and morbidity. The current study is a case of a 20-year-old male with sepsis and bilateral lung lesions infected with Multi-Drug Resistant (MDR) carbapenemase producing K. pneumoniae (KPC) showing resistance to carbapenem and polymyxin. Based on sensitivity report, patient was put on antibiotic adjuvant: Elores (ceftriaxone, sulbactam, disodium edetate) along with fluconazole for 10 days. Elores was instituted with remarkable recovery and patient was discharged.

Entities:  

Keywords:  ESBL; Elores; Enterobacteriaceae; MBL

Year:  2016        PMID: 27190808      PMCID: PMC4866106          DOI: 10.7860/JCDR/2016/17544.7697

Source DB:  PubMed          Journal:  J Clin Diagn Res        ISSN: 0973-709X


  7 in total

1.  Colistin for Klebsiella pneumoniae-associated sepsis.

Authors:  A Karabinis; E Paramythiotou; D Mylona-Petropoulou; A Kalogeromitros; N Katsarelis; F Kontopidou; I Poularas; H Malamou-Lada
Journal:  Clin Infect Dis       Date:  2003-12-04       Impact factor: 9.079

Review 2.  Emergence of Klebsiella pneumoniae carbapenemase-producing bacteria.

Authors:  Ryan S Arnold; Kerri A Thom; Saarika Sharma; Michael Phillips; J Kristie Johnson; Daniel J Morgan
Journal:  South Med J       Date:  2011-01       Impact factor: 0.954

3.  Occurrence and phenotypic detection of class A carbapenemases among Escherichia coli and Klebsiella pneumoniae blood isolates at a tertiary care center.

Authors:  Varsha Gupta; Neha Bansal; Nidhi Singla; Jagdish Chander
Journal:  J Microbiol Immunol Infect       Date:  2012-04-26       Impact factor: 4.399

4.  Severe sepsis and its impact on outcome in elderly and very elderly patients admitted in intensive care unit.

Authors:  Prashant Nasa; Deven Juneja; Omender Singh; Rohit Dang; Vikas Arora
Journal:  J Intensive Care Med       Date:  2011-03-24       Impact factor: 3.510

5.  Gram-negative versus Gram-positive bacteremia: what is more alarmin(g)?

Authors:  Irene Alexandraki; Carlos Palacio
Journal:  Crit Care       Date:  2010-05-27       Impact factor: 9.097

6.  The early antibiotic therapy in septic patients--milestone or sticking point?

Authors:  Michael Bernhard; Christoph Lichtenstern; Christian Eckmann; Markus A Weigand
Journal:  Crit Care       Date:  2014-11-30       Impact factor: 9.097

7.  Tigecycline treatment of infection caused by KPC-producing Escherichia coli in a pediatric patient.

Authors:  Xiaoxing Du; Ying Fu; Yunsong Yu
Journal:  Ann Clin Microbiol Antimicrob       Date:  2013-08-13       Impact factor: 3.944

  7 in total
  1 in total

1.  Safety and efficacy of a novel drug elores (ceftriaxone+sulbactam+disodium edetate) in the management of multi-drug resistant bacterial infections in tertiary care centers: a post-marketing surveillance study.

Authors:  Manu Chaudhary; Mohd Amin Mir; Shiekh Gazalla Ayub
Journal:  Braz J Infect Dis       Date:  2017-04-01       Impact factor: 3.257

  1 in total

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