| Literature DB >> 27190321 |
Abstract
Chronic hepatitis B virus (HBV) infection is estimated to affect >350 million people worldwide and represents a significant cause of morbidity and mortality related to cirrhosis and hepatocellular carcinoma. Mother-to-child transmission (MTCT) of HBV remains an important source of incident cases of HBV. Current barriers to eradication of incident HBV infections via MTCT include underutilization of immunoprophylaxis with hepatitis B vaccination and hepatitis B immune globulin in certain endemic regions as well as failure of immunoprophylaxis.Entities:
Keywords: hepatitis B; perinatal transmission; pregnancy; vaccination HBIG
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Year: 2016 PMID: 27190321 PMCID: PMC4889900 DOI: 10.1093/cid/ciw092
Source DB: PubMed Journal: Clin Infect Dis ISSN: 1058-4838 Impact factor: 9.079