Literature DB >> 27189703

Next-generation sequencing identifies a novel ELAVL1-TYK2 fusion gene in MOLM-16, an AML cell line highly sensitive to the PIM kinase inhibitor AZD1208.

Adriana E Tron1, Erika K Keeton1,2, Minwei Ye1, Matias Casas-Selves1,3, Huawei Chen1, Keith S Dillman1, Rosemary E Gale4, Chloe Stengel4, Michael Zinda1, David C Linch4, Zhongwu Lai1, Asim Khwaja4, Dennis Huszar1,5.   

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Year:  2016        PMID： 27189703     DOI： 10.3109/10428194.2016.1171861

Source DB:  PubMed          Journal:  Leuk Lymphoma        ISSN： 1026-8022


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  6 in total

1.  NK Cells Require Cell-Extrinsic and -Intrinsic TYK2 for Full Functionality in Tumor Surveillance and Antibacterial Immunity.

Authors:  Natalija Simonović; Agnieszka Witalisz-Siepracka; Katrin Meissl; Caroline Lassnig; Ursula Reichart; Thomas Kolbe; Matthias Farlik; Christoph Bock; Veronika Sexl; Mathias Müller; Birgit Strobl
Journal:  J Immunol       Date:  2019-02-04       Impact factor: 5.422

2.  Exploring the oncogenic and therapeutic target potential of the MYB-TYK2 fusion gene in B-cell acute lymphoblastic leukemia.

Authors:  Paniz Tavakoli Shirazi; Laura N Eadie; Susan L Heatley; Elyse C Page; Maxime François; Timothy P Hughes; David Yeung; Deborah L White
Journal:  Cancer Gene Ther       Date:  2022-01-12       Impact factor: 5.854

3.  FLT3-ITD induces expression of Pim kinases through STAT5 to confer resistance to the PI3K/Akt pathway inhibitors on leukemic cells by enhancing the mTORC1/Mcl-1 pathway.

Authors:  Keigo Okada; Ayako Nogami; Shinya Ishida; Hiroki Akiyama; Cheng Chen; Yoshihiro Umezawa; Osamu Miura
Journal:  Oncotarget       Date:  2017-12-04

Review 4.  TYK2: An Upstream Kinase of STATs in Cancer.

Authors:  Katharina Wöss; Natalija Simonović; Birgit Strobl; Sabine Macho-Maschler; Mathias Müller
Journal:  Cancers (Basel)       Date:  2019-11-05       Impact factor: 6.639

5.  Dependency on the TYK2/STAT1/MCL1 axis in anaplastic large cell lymphoma.

Authors:  Lukas Kenner; Olaf Merkel; Nicole Prutsch; Elisabeth Gurnhofer; Tobias Suske; Huan Chang Liang; Michaela Schlederer; Simone Roos; Lawren C Wu; Ingrid Simonitsch-Klupp; Andrea Alvarez-Hernandez; Christoph Kornauth; Dario A Leone; Jasmin Svinka; Robert Eferl; Tanja Limberger; Astrid Aufinger; Nitesh Shirsath; Peter Wolf; Thomas Hielscher; Christina Sternberg; Fritz Aberger; Johannes Schmoellerl; Dagmar Stoiber; Birgit Strobl; Ulrich Jäger; Philipp B Staber; Florian Grebien; Richard Moriggl; Mathias Müller; Giorgio G Inghirami; Takaomi Sanda; A Thomas Look; Suzanne D Turner
Journal:  Leukemia       Date:  2018-08-21       Impact factor: 11.528

6.  Tyk2 is a tumor suppressor in colorectal cancer.

Authors:  Stefan Moritsch; Bernadette Mödl; Irene Scharf; Lukas Janker; Daniela Zwolanek; Gerald Timelthaler; Emilio Casanova; Maria Sibilia; Thomas Mohr; Lukas Kenner; Dietmar Herndler-Brandstetter; Christopher Gerner; Mathias Müller; Birgit Strobl; Robert Eferl
Journal:  Oncoimmunology       Date:  2022-09-26       Impact factor: 7.723
  6 in total

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