Literature DB >> 27188741

Meta-analysis of traditional herbal medicine in the treatment of nonalcoholic fatty liver disease.

H Peng1, Y He1, G Zheng2, W Zhang3, Z Yao1, W Xie4.   

Abstract

Traditional Chinese herbal medicine (TCM) has been found effective for nonalcoholic fatty liver disease (NAFLD) based on its unique theory system and substantial herb remedies. The aim of this meta-analysis was to evaluate the efficiency and safety of one of the TCM, Danshen in the treatment of NAFLD. Seven English and Chinese databases were searched from inceptions to December 2015. RCTs which compared Danshen with placebo in adult patients with NAFLD were included. Totally, 8 RCTs with a total of 800 patients were identified. The results showed that compared with placebo, Danshen had increased total effectiveness rate, lower level of ALT, AST, TC and TG, LDL and higher level of liver/spleen computed tomography ratio. The present meta-analysis suggests that Danshen may have positive effects on nonalcoholic fatty liver disease. Future multicenter large-sample randomized clinical trials are still needed to confirm the efficacy and safety of our study.

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Year:  2016        PMID： 27188741

Source DB:  PubMed          Journal:  Cell Mol Biol (Noisy-le-grand)        ISSN： 0145-5680            Impact factor:   1.770


  8 in total

1.  A Biomedical Investigation of the Hepatoprotective Effect of Radix salviae miltiorrhizae and Network Pharmacology-Based Prediction of the Active Compounds and Molecular Targets.

Authors:  Ming Hong; Sha Li; Ning Wang; Hor-Yue Tan; Fan Cheung; Yibin Feng
Journal:  Int J Mol Sci       Date:  2017-03-13       Impact factor: 5.923

2.  Induced overexpression of CD44 associated with resistance to apoptosis on DNA damage response in human head and neck squamous cell carcinoma cells.

Authors:  Emika Ohkoshi; Naoki Umemura
Journal:  Int J Oncol       Date:  2016-12-28       Impact factor: 5.650

Review 3.  Herbal Medicine in the Treatment of Non-Alcoholic Fatty Liver Diseases-Efficacy, Action Mechanism, and Clinical Application.

Authors:  Yu Xu; Wei Guo; Cheng Zhang; Feiyu Chen; Hor Yue Tan; Sha Li; Ning Wang; Yibin Feng
Journal:  Front Pharmacol       Date:  2020-05-12       Impact factor: 5.810

Review 4.  Salvia miltiorrhiza Bge. (Danshen) in the Treating Non-alcoholic Fatty Liver Disease Based on the Regulator of Metabolic Targets.

Authors:  Jie Liu; Yun Shi; Daiyin Peng; Lei Wang; Nianjun Yu; Guokai Wang; Weidong Chen
Journal:  Front Cardiovasc Med       Date:  2022-04-22

5.  Hepatoprotective Effects of a Functional Formula of Three Chinese Medicinal Herbs: Experimental Evidence and Network Pharmacology-Based Identification of Mechanism of Action and Potential Bioactive Components.

Authors:  Sha Li; Ning Wang; Ming Hong; Hor-Yue Tan; Guofeng Pan; Yibin Feng
Journal:  Molecules       Date:  2018-02-07       Impact factor: 4.411

6.  Investigation on the Use of Traditional Chinese Medicine for Polycystic Ovary Syndrome in a Nationwide Prescription Database in Taiwan.

Authors:  Wan-Ting Liao; Jen-Huai Chiang; Chia-Jung Li; Ming-Tsung Lee; Cheng-Chiung Su; Hung-Rong Yen
Journal:  J Clin Med       Date:  2018-07-22       Impact factor: 4.241

7.  Nutraceutical Approach to Non-Alcoholic Fatty Liver Disease (NAFLD): The Available Clinical Evidence.

Authors:  Arrigo F G Cicero; Alessandro Colletti; Stefano Bellentani
Journal:  Nutrients       Date:  2018-08-23       Impact factor: 5.717

Review 8.  The Impacts of Herbal Medicines and Natural Products on Regulating the Hepatic Lipid Metabolism.

Authors:  Sha Li; Yu Xu; Wei Guo; Feiyu Chen; Cheng Zhang; Hor Yue Tan; Ning Wang; Yibin Feng
Journal:  Front Pharmacol       Date:  2020-03-24       Impact factor: 5.810
  8 in total

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