| Literature DB >> 27186648 |
Ratsami Lekphrom1, Kwanjai Kanokmedhakul1, Watchara Sangsopha, Somdej Kanokmedhakul1.
Abstract
A new coumarin, minutuminolate (1), together with eleven known coumarins (2-12), was isolated from the roots of Micromelum minutum. The structures of these compounds were established on the basis of their 1D and 2D NMR spectroscopic data. Compounds 2, 5, 10, 11 and 12 showed cytotoxicity against KB cell line. In addition, compounds 2, 3, 4, 7, 11 and 12 also showed weak cytotoxicity against NCI-H187 cell line.Entities:
Keywords: Micromelum minutum; Rutaceae; coumarin; cytotoxicity
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Year: 2016 PMID： 27186648 DOI： 10.1080/14786419.2016.1185720
Source DB: PubMed Journal: Nat Prod Res ISSN： 1478-6419 Impact factor: 2.861