Literature DB >> 27185009

Accidental hypothermia in severe trauma.

Fanny Vardon1, Ségolène Mrozek1, Thomas Geeraerts2, Olivier Fourcade1.   

Abstract

Hypothermia, along with acidosis and coagulopathy, is part of the lethal triad that worsen the prognosis of severe trauma patients. While accidental hypothermia is easy to identify by a simple measurement, it is no less pernicious if it is not detected or treated in the initial phase of patient care. It is a multifactorial process and is a factor of mortality in severe trauma cases. The consequences of hypothermia are many: it modifies myocardial contractions and may induce arrhythmias; it contributes to trauma-induced coagulopathy; from an immunological point of view, it diminishes inflammatory response and increases the chance of pneumonia in the patient; it inhibits the elimination of anaesthetic drugs and can complicate the calculation of dosing requirements; and it leads to an over-estimation of coagulation factor activities. This review will detail the pathophysiological consequences of hypothermia, as well as the most recent principle recommendations in dealing with it.
Copyright © 2016. Published by Elsevier Masson SAS.

Entities:  

Keywords:  Coagulopathy; Haemostasis; Hypothermia; Mortality; Polytrauma

Mesh:

Year:  2016        PMID: 27185009     DOI: 10.1016/j.accpm.2016.05.001

Source DB:  PubMed          Journal:  Anaesth Crit Care Pain Med        ISSN: 2352-5568            Impact factor:   4.132


  5 in total

1.  Hypothermia-Associated Coagulopathy: A Comparison of Viscoelastic Monitoring, Platelet Function, and Real Time Live Confocal Microscopy at Low Blood Temperatures, an in vitro Experimental Study.

Authors:  Bernd Wallner; Bettina Schenk; Martin Hermann; Peter Paal; Markus Falk; Giacomo Strapazzon; Wenjun Z Martini; Hermann Brugger; Dietmar Fries
Journal:  Front Physiol       Date:  2020-07-14       Impact factor: 4.566

Review 2.  Effect of hypothermia on haemostasis and bleeding risk: a narrative review.

Authors:  Thomas Kander; Ulf Schött
Journal:  J Int Med Res       Date:  2019-08       Impact factor: 1.671

3.  Hypothermia Induced Impairment of Platelets: Assessment With Multiplate vs. ROTEM-An In Vitro Study.

Authors:  Bernd Wallner; Bettina Schenk; Peter Paal; Markus Falk; Giacomo Strapazzon; Wenjun Z Martini; Hermann Brugger; Dietmar Fries
Journal:  Front Physiol       Date:  2022-03-29       Impact factor: 4.566

4.  Regional hypothermia attenuates secondary-injury caused by time-out application of tourniquets following limb fragments injury combined with hemorrhagic shock.

Authors:  Changmei Weng; Kai Lan; Tao Li; Liangchao Zhang; Jianmin Wang; Xinan Lai
Journal:  Scand J Trauma Resusc Emerg Med       Date:  2019-11-21       Impact factor: 2.953

Review 5.  Is prehospital use of active external warming dangerous for patients with accidental hypothermia: a systematic review.

Authors:  Sigurd Mydske; Øyvind Thomassen
Journal:  Scand J Trauma Resusc Emerg Med       Date:  2020-08-10       Impact factor: 2.953

  5 in total

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