| Literature DB >> 27183838 |
Magda Vieira Benavides1, Tad S Sonstegard2, Curtis Van Tassell3.
Abstract
Genetic markers for sheep resistance to gastrointestinal parasites have long been sought by the livestock industry as a way to select more resistant individuals and to help farmers reduce parasite transmission by identifying and removing high egg shedders from the flock. Polymorphisms related to the major histocompatibility complex and interferon (IFN)-γ genes have been the most frequently reported markers associated with infection. Recently, a new picture is emerging from genome-wide studies, showing that not only immune mechanisms are important determinants of host resistance but that gastrointestinal mucus production and hemostasis pathways may also play a role.Entities:
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Year: 2016 PMID： 27183838 DOI： 10.1016/j.pt.2016.03.007
Source DB: PubMed Journal: Trends Parasitol ISSN： 1471-4922