| Literature DB >> 27183562 |
Johannes Krause1, Svante Pääbo2.
Abstract
At its core, genetics is a historical discipline. Mutations are passed on from generation to generation and accumulate as a result of chance as well as of selection within and between populations and species. However, until recently, geneticists were confined to the study of present-day genetic variation and could only indirectly make inferences about the historical processes that resulted in the variation in present-day gene pools. This "time trap" has now been overcome thanks to the ability to analyze DNA extracted from ancient remains, and this is about to revolutionize several aspects of genetics.Keywords: ancient DNA; evolution
Mesh:
Year: 2016 PMID: 27183562 PMCID: PMC4858805 DOI: 10.1534/genetics.116.187856
Source DB: PubMed Journal: Genetics ISSN: 0016-6731 Impact factor: 4.562