Eda Albayrak1, Hatice Yılmaz Dogru2, Zafer Ozmen3, Ayşegül Altunkas4, Tugce Ozlem Kalayci5, Mehmet Fatih Inci6, Sadık Server7, Fitnet Sonmezgoz8, Fatma Aktas9, Osman Demir10. 1. Department of Radiology, Gaziosmanpasa University, Medical Faculty, Tokat, Turkey. Electronic address: edalbayrak1@hotmail.com. 2. Department of Obstetrics and Gynecology, Gaziosmanpasa University, Medical Faculty, Tokat, Turkey. Electronic address: hatice_yilmaz47@hotmail.com. 3. Department of Radiology, Gaziosmanpasa University, Medical Faculty, Tokat, Turkey. Electronic address: doktor.zafer@mynet.com. 4. Department of Radiology, Gaziosmanpasa University, Medical Faculty, Tokat, Turkey. Electronic address: aaltunkas@hotmail.com. 5. Department of Radiology, Izmir Katip Celebi University Ataturk Training and Research Hospital, Izmir, Turkey. Electronic address: doktorozlemtugce@gmail.com. 6. Department of Radiology, Izmir Katip Celebi University Ataturk Training and Research Hospital, Izmir, Turkey. Electronic address: drfatihinci@gmail.com. 7. Department of Radiology, Istanbul Bilim University, Medical Faculty, Şişli Florance Nightingale Hospital, Istanbul, Turkey. Electronic address: servergreen@gmail.com. 8. Department of Radiology, Gaziosmanpasa University, Medical Faculty, Tokat, Turkey. Electronic address: fitnats@gmail.com. 9. Department of Radiology, Gaziosmanpasa University, Medical Faculty, Tokat, Turkey. Electronic address: fatmakokcu79@hotmail.com. 10. Department of Biostatistics, Gaziosmanpasa University, Medical Faculty, Tokat, Turkey. Electronic address: mosmandemir@hotmail.com.
Abstract
PURPOSE: The aim of this study is to investigate the effectiveness of placental strain ratio (SR) values measured by real-time sonoelastography (SE) in the second trimester in the prediction of spontaneous preterm birth (sPTB). METHODS: This study included 70 pregnant women who applied to our clinic for routine second-trimester screening. Placental SR measurements were performed with the SE method. Two different SR measurements were performed by taking two different tissues as references. The SR value measured when taking the rectus abdominis muscle as a reference was termed the muscle-to-placenta strain ratio (MPSR), while the SR value measured when taking subcutaneous tissue as a reference was termed the fat-to-placenta strain ratio (FPSR). Women whose gestational age at birth was less than 37 weeks 0 days were accepted as sPTB. The association between gestational age at birth and MPSR and FPSR was investigated. Receiver operating characteristics analysis was used to calculate the sensitivity and specificity of the elastographic outcomes. RESULTS: There was a low-level negative correlation between MPSR and gestational age at birth (r=-0.300, P=.012) and there was a moderate-level negative correlation between FPSR and gestational age at birth (r=-0.513, P<.001). The multivariate linear regression analysis showed that the FPSR (β=0.609, P=.002) was the significant predictor for the sPTB. CONCLUSIONS: Our data indicate that the FPSR value measured with real-time SE in the second trimester of pregnancy may be effective in the prediction of sPTB.
PURPOSE: The aim of this study is to investigate the effectiveness of placental strain ratio (SR) values measured by real-time sonoelastography (SE) in the second trimester in the prediction of spontaneous preterm birth (sPTB). METHODS: This study included 70 pregnant women who applied to our clinic for routine second-trimester screening. Placental SR measurements were performed with the SE method. Two different SR measurements were performed by taking two different tissues as references. The SR value measured when taking the rectus abdominis muscle as a reference was termed the muscle-to-placenta strain ratio (MPSR), while the SR value measured when taking subcutaneous tissue as a reference was termed the fat-to-placenta strain ratio (FPSR). Women whose gestational age at birth was less than 37 weeks 0 days were accepted as sPTB. The association between gestational age at birth and MPSR and FPSR was investigated. Receiver operating characteristics analysis was used to calculate the sensitivity and specificity of the elastographic outcomes. RESULTS: There was a low-level negative correlation between MPSR and gestational age at birth (r=-0.300, P=.012) and there was a moderate-level negative correlation between FPSR and gestational age at birth (r=-0.513, P<.001). The multivariate linear regression analysis showed that the FPSR (β=0.609, P=.002) was the significant predictor for the sPTB. CONCLUSIONS: Our data indicate that the FPSR value measured with real-time SE in the second trimester of pregnancy may be effective in the prediction of sPTB.