Literature DB >> 27182665

Cysteine containing dipeptides show a metal specificity that matches the composition of seawater.

Luca Belmonte1, Daniele Rossetto1, Michele Forlin1, Simone Scintilla1, Claudia Bonfio1, Sheref S Mansy1.   

Abstract

Model prebiotic dipeptide sequences were identified by bioinformatics and DFT and molecular dynamics calculations. The peptides were then synthesized and evaluated for metal affinity and specificity. Cysteine containing dipeptides were not associated with metal affinities that followed the Irving-Williams series but did follow the concentration trends found in seawater.

Entities:  

Year:  2016        PMID： 27182665     DOI： 10.1039/c6cp00608f

Source DB:  PubMed          Journal:  Phys Chem Chem Phys        ISSN： 1463-9076            Impact factor:   3.676


  3 in total

1.  Prebiotic Environments with Mg2+ and Thiophilic Metal Ions Increase the Thermal Stability of Cysteine and Non-cysteine Peptides.

Authors:  Daniele Rossetto; Luca Valer; Noël Yeh Martín; Graziano Guella; Yayoi Hongo; Sheref S Mansy
Journal:  ACS Earth Space Chem       Date:  2022-04-15       Impact factor: 3.556

Review 2.  Progress in synthesizing protocells.

Authors:  O Duhan Toparlak; Sheref S Mansy
Journal:  Exp Biol Med (Maywood)       Date:  2018-12-03

3.  Cysteine and iron accelerate the formation of ribose-5-phosphate, providing insights into the evolutionary origins of the metabolic network structure.

Authors:  Gabriel Piedrafita; Sreejith J Varma; Cecilia Castro; Christoph B Messner; Lukasz Szyrwiel; Julian L Griffin; Markus Ralser
Journal:  PLoS Biol       Date:  2021-12-03       Impact factor: 8.029
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.