Literature DB >> 27182513

EXPERIENCE WITH MANAGING SOLID KIDNEY TUMOURS IN COTONOU, BENIN REPUBLIC.

Dgj Avakoudjo1, P P Hounnasso1, M T Traore1, G Natchagandé1, A K Pare1, R Tore-Sanni1, M M Agounkpé1, S Ouédraogo1, F Soumanou1, A Gouissi1.   

Abstract

BACKGROUND: Kidney cancer is the third most common urological tumour. Diagnosis is made in most cases at an advanced stage of the disease in our setting. AIM &
OBJECTIVES: The aim of this work was to describe the management of solid tumors of the kidney and the outcome at the National University Hospital, Cotonou, Benin Republic, from January 2008 to December 2014. PATIENTS &
METHODS: This is a retrospective, descriptive study conducted at the Clinic of Urology and Andrology at the National University Hospital CNHU-Hubert Koutoukou MAGA in Cotonou, Benin Republic. We included patients managed for solid kidney tumours from January 2008 to December 2014. The demographics, clinical presentations, management and outcome were recorded and the data obtained were analyzed using Epi info 3.2.2.
RESULTS: Hospital frequency of solid renal mass was 1.9% with a mean age of 54 years and sex ratio of men to women of 1.6. Hematuria, back pain and lumbar mass were the most frequent clinical presentation found in 79.5% of cases. In all, 5% presented at an early stage while 95% presented at a late stage. Diagnosis was based on imaging; histopathological examination was requested in all the case though some could not afford the cost. Radical nephrectomy was performed in 51.5% of cases.The non- operated cases were those whose poor general condition as well as those who could not afford the procedure. Undifferentiated adenocarcinoma was the predominant pathological type found in 78% of operated cases. No patients underwent other treatments such as radiation therapy, immunotherapy or chemotherapy. Mortality occured in 10 cases including 1 intra operative death, 3 patients died in the early post operative period due to respiratory distress and 7 patients died from metatstasis discovered post operatively.
CONCLUSION: This study has shown that majority of patients with solid renal tumours in this environment present late with advanced stages of the disease. The absence of the necessary investigative equipment, poverty and absence of adjuvant and adjunct therapeutic facilities make the treatment outcome poor.

Entities:  

Keywords:  Advanced disease; Benin Republic; Late presentation; Poor treatment outcome; Poverty; Solid Kidney tumors

Year:  2014        PMID: 27182513      PMCID: PMC4866726     

Source DB:  PubMed          Journal:  J West Afr Coll Surg        ISSN: 2276-6944


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Journal:  Cancer Manag Res       Date:  2022-05-30       Impact factor: 3.602

Review 2.  Management of Renal Cell Carcinoma-Current Practice in Sub-Saharan Africa.

Authors:  Ayun Cassell; Mohamed Jalloh; Bashir Yunusa; Medina Ndoye; Mouhamadou M Mbodji; Abdourahmane Diallo; Saint Charles Kouka; Issa Labou; Lamine Niang; Serigne M Gueye
Journal:  J Kidney Cancer VHL       Date:  2019-12-02
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