Literature DB >> 27182206

Ingestible Biosensors for Real-Time Medical Adherence Monitoring: MyTMed.

Peter R Chai1, Rochelle K Rosen2, Edward W Boyer1.   

Abstract

Medication nonadherence complicates the management and treatment of chronic disease. Nonadherence to medications is associated with significant mortality, accelerated disease progression, and increased health care costs. My/Treatment/Medication (MyTMed) is a novel adherence monitoring system that obtains direct measures of medication adherence/nonadherence. MyTMed consists of 1) a "digital pill" with a radiofrequency emitter that activates on contact with gastric pH; 2) a relay Hub that captures the radiofrequency signal and transmits it to 3) a cloud based server that connects patient and physicians via a bidirectional interface. In our increasingly mobile world, MyTMed is able to provide medication ingestion data and deliver interventions in real time that support adherence. We describe the patient-centered design of MyTMed as well as the behavioral theory supporting the interface architecture.

Entities:  

Year:  2016        PMID： 27182206      PMCID： PMC4862950          DOI： 10.1109/HICSS.2016.426

Source DB:  PubMed          Journal:  Proc Annu Hawaii Int Conf Syst Sci        ISSN： 1530-1605


  28 in total

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Journal:  J Gen Intern Med       Date:  2002-05       Impact factor: 5.128

2.  Preliminary efforts directed toward the detection of craving of illicit substances: the iHeal project.

Authors:  Edward W Boyer; Rich Fletcher; Richard J Fay; David Smelson; Douglas Ziedonis; Rosalind W Picard
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3.  A digital health solution for using and managing medications: wirelessly observed therapy.

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4.  Drug use and medication adherence among HIV-1 infected individuals.

Authors:  Charles H Hinkin; Terry R Barclay; Steven A Castellon; Andrew J Levine; Ramani S Durvasula; Sarah D Marion; Hector F Myers; Douglas Longshore
Journal:  AIDS Behav       Date:  2007-03

5.  Real-time mobile detection of drug use with wearable biosensors: a pilot study.

Authors:  Stephanie Carreiro; David Smelson; Megan Ranney; Keith J Horvath; R W Picard; Edwin D Boudreaux; Rashelle Hayes; Edward W Boyer
Journal:  J Med Toxicol       Date:  2015-03

Review 6.  A systematic review of barriers to medication adherence in the elderly: looking beyond cost and regimen complexity.

Authors:  Walid F Gellad; Jerry L Grenard; Zachary A Marcum
Journal:  Am J Geriatr Pharmacother       Date:  2011-02

Review 7.  Health behavior models in the age of mobile interventions: are our theories up to the task?

Authors:  William T Riley; Daniel E Rivera; Audie A Atienza; Wendy Nilsen; Susannah M Allison; Robin Mermelstein
Journal:  Transl Behav Med       Date:  2011-03       Impact factor: 3.046

Review 8.  Saquinavir soft-gel capsule formulation. A review of its use in patients with HIV infection.

Authors:  C M Perry; S Noble
Journal:  Drugs       Date:  1998-03       Impact factor: 9.546

Review 9.  The administration of L-thyroxine as soft gel capsule or liquid solution.

Authors:  Roberto Vita; Poupak Fallahi; Alessandro Antonelli; Salvatore Benvenga
Journal:  Expert Opin Drug Deliv       Date:  2014-06-04       Impact factor: 6.648

Review 10.  A review of health behaviour theories: how useful are these for developing interventions to promote long-term medication adherence for TB and HIV/AIDS?

Authors:  Salla Munro; Simon Lewin; Tanya Swart; Jimmy Volmink
Journal:  BMC Public Health       Date:  2007-06-11       Impact factor: 3.295
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  9 in total

1.  Oxycodone Ingestion Patterns in Acute Fracture Pain With Digital Pills.

Authors:  Peter R Chai; Stephanie Carreiro; Brendan J Innes; Brittany Chapman; Kristin L Schreiber; Robert R Edwards; Adam W Carrico; Edward W Boyer
Journal:  Anesth Analg       Date:  2017-12       Impact factor: 5.108

Review 2.  Integrating Personalized Technology in Toxicology: Sensors, Smart Glass, and Social Media Applications in Toxicology Research.

Authors:  Stephanie Carreiro; Peter R Chai; Jennifer Carey; Brittany Chapman; Edward W Boyer
Journal:  J Med Toxicol       Date:  2017-04-12

3.  Short Communication: Bioequivalence of Tenofovir Component of Tenofovir/Rilpivirine/Emtricitabine in Digital Pills.

Authors:  Peter R Chai; Luis M Pereira; Guruprasad D Jambaulikar; Adam W Carrico; Conall O'Cleirigh; Kenneth H Mayer; Edward W Boyer
Journal:  AIDS Res Hum Retroviruses       Date:  2019-03-13       Impact factor: 2.205

4.  Long-Term Stability of the Electronic Sensor Component of a Digital Pill System in Real-World Storage Settings.

Authors:  Peter R Chai; Georgia Goodman; Majo J Bustamante; Yassir Mohamed; Jose Castillo-Mancilla; Edward W Boyer; Kenneth H Mayer; Rochelle K Rosen; Susan L Baumgartner; Eric Buffkin; Conall O'Cleirigh
Journal:  J Pharm Technol       Date:  2021-01-06

5.  Antiretroviral Therapy Adherence Interruptions Are Associated With Systemic Inflammation Among Ugandans Who Achieved Viral Suppression.

Authors:  Nicholas Musinguzi; Jose Castillo-Mancilla; Mary Morrow; Helen Byakwaga; Samantha Mawhinney; Tricia H Burdo; Yap Boum; Conrad Muzoora; Bosco M Bwana; Mark J Siedner; Jeffrey N Martin; Peter W Hunt; David R Bangsberg; Jessica E Haberer
Journal:  J Acquir Immune Defic Syndr       Date:  2019-12-01       Impact factor: 3.731

Review 6.  Review of glaucoma medication adherence monitoring in the digital health era.

Authors:  Alaa Erras; Bita Shahrvini; Robert N Weinreb; Sally L Baxter
Journal:  Br J Ophthalmol       Date:  2021-04-15       Impact factor: 5.908

Review 7.  Technologies for Medication Adherence Monitoring and Technology Assessment Criteria: Narrative Review.

Authors:  Madilyn Mason; Youmin Cho; Jessica Rayo; Yang Gong; Marcelline Harris; Yun Jiang
Journal:  JMIR Mhealth Uhealth       Date:  2022-03-10       Impact factor: 4.947

8.  Design and Delivery of Real-Time Adherence Data to Men Who Have Sex with Men Using Antiretroviral Pre-exposure Prophylaxis via an Ingestible Electronic Sensor.

Authors:  Peter R Chai; Georgia Goodman; Majo Bustamante; Lizette Mendez; Yassir Mohamed; Kenneth H Mayer; Edward W Boyer; Rochelle K Rosen; Conall O'Cleirigh
Journal:  AIDS Behav       Date:  2020-11-21

9.  Digitalized Human Organoid for Wireless Phenotyping.

Authors:  Masaki Kimura; Momoko Azuma; Ran-Ran Zhang; Wendy Thompson; Christopher N Mayhew; Takanori Takebe
Journal:  iScience       Date:  2018-05-31
  9 in total

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