Trille Kjaer1, Susanne Oksbjerg Dalton2, Elo Andersen3, Randi Karlsen2, Anni Linnet Nielsen3, Merete Kjaer Hansen4, Kirsten Frederiksen4, Christoffer Johansen5. 1. Danish Cancer Society Research Center, Copenhagen, Denmark. Electronic address: trille@cancer.dk. 2. Danish Cancer Society Research Center, Copenhagen, Denmark. 3. Department of Oncology, Herlev Hospital, University of Copenhagen, Denmark. 4. Department of Statistics, Bioinformatics and Registry, Danish Cancer Society Research Center, Copenhagen, Denmark. 5. Danish Cancer Society Research Center, Copenhagen, Denmark; Department of Oncology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
Abstract
BACKGROUND AND PURPOSE: To test the effect of longitudinal feedback on late effects reported by survivors of head-and-neck cancer (HNC) to clinicians during regular follow-up. MATERIAL AND METHODS: A total of 266 participants were sequentially assigned to either control or intervention group and filled in electronic versions of the EORTC QLQ C-30, H&N35, HADS and a study-specific list of symptoms at up to two consecutive follow-up visits. Participants' symptoms displayed according to severity were provided to the clinician for the intervention group but not for the control group. Linear mixed-effects models were used to examine the number of symptoms assessed by clinicians (primary outcome). Multivariate linear regression models examined participants' long-term symptom control and QoL (secondary outcome). RESULTS: More symptoms were assessed by clinicians in the intervention group at all three visits (P<0.001, <0.001, and P=0.04). No effect was observed on most patient outcomes. When prompted by patient-reported outcomes at consultations, clinicians and patients were in better agreement about the occurrence of severe symptoms at all three visits. CONCLUSION: Timely patient-reported outcomes to clinicians in routine follow-up of HNC survivors enhanced clinicians' rates of assessment of late symptoms. Giving reports of patient-reported outcome to clinicians had limited impact on participants' QoL or symptom burden.
RCT Entities:
BACKGROUND AND PURPOSE: To test the effect of longitudinal feedback on late effects reported by survivors of head-and-neck cancer (HNC) to clinicians during regular follow-up. MATERIAL AND METHODS: A total of 266 participants were sequentially assigned to either control or intervention group and filled in electronic versions of the EORTCQLQ C-30, H&N35, HADS and a study-specific list of symptoms at up to two consecutive follow-up visits. Participants' symptoms displayed according to severity were provided to the clinician for the intervention group but not for the control group. Linear mixed-effects models were used to examine the number of symptoms assessed by clinicians (primary outcome). Multivariate linear regression models examined participants' long-term symptom control and QoL (secondary outcome). RESULTS: More symptoms were assessed by clinicians in the intervention group at all three visits (P<0.001, <0.001, and P=0.04). No effect was observed on most patient outcomes. When prompted by patient-reported outcomes at consultations, clinicians and patients were in better agreement about the occurrence of severe symptoms at all three visits. CONCLUSION: Timely patient-reported outcomes to clinicians in routine follow-up of HNC survivors enhanced clinicians' rates of assessment of late symptoms. Giving reports of patient-reported outcome to clinicians had limited impact on participants' QoL or symptom burden.
Authors: Christina Hague; Marianne Aznar; Lei Dong; Alireza Fotouhi-Ghiam; Lip Wai Lee; Taoran Li; Alexander Lin; Matthew Lowe; John N Lukens; Andrew McPartlin; Shannon O'Reilly; Nick Slevin; Samuel Swisher-Mcclure; David Thomson; Marcel Van Herk; Catharine West; Wei Zou; Boon-Keng Kevin Teo Journal: Br J Radiol Date: 2019-12-23 Impact factor: 3.039
Authors: M Sean Peach; Daniel M Trifiletti; Carolyn Vachani; Karen Arnold-Korzeniowski; Christina Bach; Margaret Hampshire; James M Metz; Christine E Hill-Kayser Journal: Patient Relat Outcome Meas Date: 2018-07-27