Literature DB >> 27177653

Application of Mass Cytometry (CyTOF) for Functional and Phenotypic Analysis of Natural Killer Cells.

Alexander W Kay1, Dara M Strauss-Albee2, Catherine A Blish3,4.   

Abstract

Mass cytometry is a novel platform for high-dimensional phenotypic and functional analysis of single cells. This system uses elemental metal isotopes conjugated to monoclonal antibodies to evaluate up to 42 parameters simultaneously on individual cells with minimal overlap between channels. The platform can be customized for analysis of both phenotypic and functional markers. Here, we will describe methods to stain, collect, and analyze intracellular functional markers and surface phenotypic markers on natural killer cells.

Entities:  

Keywords:  CyTOF; Flow cytometry; Intracellular cytokine staining; Mass cytometry; Natural killer cell

Mesh：

Substances：

Year:  2016        PMID： 27177653      PMCID： PMC5304457          DOI： 10.1007/978-1-4939-3684-7_2

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN： 1064-3745


  12 in total

1.  Mass cytometry: protocol for daily tuning and running cell samples on a CyTOF mass cytometer.

Authors:  Michael D Leipold; Holden T Maecker
Journal:  J Vis Exp       Date:  2012-11-02       Impact factor: 1.355

2.  Cytometry by time-of-flight shows combinatorial cytokine expression and virus-specific cell niches within a continuum of CD8+ T cell phenotypes.

Authors:  Evan W Newell; Natalia Sigal; Sean C Bendall; Garry P Nolan; Mark M Davis
Journal:  Immunity       Date:  2012-01-27       Impact factor: 31.745

3.  Automated identification of stratifying signatures in cellular subpopulations.

Authors:  Robert V Bruggner; Bernd Bodenmiller; David L Dill; Robert J Tibshirani; Garry P Nolan
Journal:  Proc Natl Acad Sci U S A       Date:  2014-06-16       Impact factor: 11.205

4.  Genetic and environmental determinants of human NK cell diversity revealed by mass cytometry.

Authors:  Amir Horowitz; Dara M Strauss-Albee; Michael Leipold; Jessica Kubo; Neda Nemat-Gorgani; Ozge C Dogan; Cornelia L Dekker; Sally Mackey; Holden Maecker; Gary E Swan; Mark M Davis; Paul J Norman; Lisbeth A Guethlein; Manisha Desai; Peter Parham; Catherine A Blish
Journal:  Sci Transl Med       Date:  2013-10-23       Impact factor: 17.956

5.  Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum.

Authors:  Sean C Bendall; Erin F Simonds; Peng Qiu; El-ad D Amir; Peter O Krutzik; Rachel Finck; Robert V Bruggner; Rachel Melamed; Angelica Trejo; Olga I Ornatsky; Robert S Balderas; Sylvia K Plevritis; Karen Sachs; Dana Pe'er; Scott D Tanner; Garry P Nolan
Journal:  Science       Date:  2011-05-06       Impact factor: 47.728

6.  viSNE enables visualization of high dimensional single-cell data and reveals phenotypic heterogeneity of leukemia.

Authors:  El-ad David Amir; Kara L Davis; Michelle D Tadmor; Erin F Simonds; Jacob H Levine; Sean C Bendall; Daniel K Shenfeld; Smita Krishnaswamy; Garry P Nolan; Dana Pe'er
Journal:  Nat Biotechnol       Date:  2013-05-19       Impact factor: 54.908

7.  Coordinated regulation of NK receptor expression in the maturing human immune system.

Authors:  Dara M Strauss-Albee; Amir Horowitz; Peter Parham; Catherine A Blish
Journal:  J Immunol       Date:  2014-10-06       Impact factor: 5.422

8.  Normalization of mass cytometry data with bead standards.

Authors:  Rachel Finck; Erin F Simonds; Astraea Jager; Smita Krishnaswamy; Karen Sachs; Wendy Fantl; Dana Pe'er; Garry P Nolan; Sean C Bendall
Journal:  Cytometry A       Date:  2013-03-19       Impact factor: 4.355

9.  A platinum-based covalent viability reagent for single-cell mass cytometry.

Authors:  Harris G Fienberg; Erin F Simonds; Wendy J Fantl; Garry P Nolan; Bernd Bodenmiller
Journal:  Cytometry A       Date:  2012-05-10       Impact factor: 4.355

10.  Extracting a cellular hierarchy from high-dimensional cytometry data with SPADE.

Authors:  Peng Qiu; Erin F Simonds; Sean C Bendall; Kenneth D Gibbs; Robert V Bruggner; Michael D Linderman; Karen Sachs; Garry P Nolan; Sylvia K Plevritis
Journal:  Nat Biotechnol       Date:  2011-10-02       Impact factor: 54.908
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  25 in total

Review 1.  Systems immunology: just getting started.

Authors:  Mark M Davis; Cristina M Tato; David Furman
Journal:  Nat Immunol       Date:  2017-06-20       Impact factor: 25.606

Review 2.  The search for drug-targetable diagnostic, prognostic and predictive biomarkers in chronic graft-versus-host disease.

Authors:  Hong-Gang Ren; Djamilatou Adom; Sophie Paczesny
Journal:  Expert Rev Clin Immunol       Date:  2018-04-19       Impact factor: 4.473

Review 3.  Proteomic Approaches to Decipher Mechanisms Underlying Pathogenesis in Multiple Sclerosis Patients.

Authors:  Vaibhav Singh; Ajai Tripathi; Ranjan Dutta
Journal:  Proteomics       Date:  2019-06-21       Impact factor: 3.984

4.  Mass cytometry analysis of immune cells in the brain.

Authors:  Ben Korin; Tania Dubovik; Asya Rolls
Journal:  Nat Protoc       Date:  2018-01-25       Impact factor: 13.491

5.  Tyramide-conjugated DNA barcodes enable signal amplification for multiparametric CODEX imaging.

Authors:  Paul D Simonson; Itzel Valencia; Sanjay S Patel
Journal:  Commun Biol       Date:  2022-06-27

6.  Differential Induction of IFN-α and Modulation of CD112 and CD54 Expression Govern the Magnitude of NK Cell IFN-γ Response to Influenza A Viruses.

Authors:  Lisa M Kronstad; Christof Seiler; Rosemary Vergara; Susan P Holmes; Catherine A Blish
Journal:  J Immunol       Date:  2018-08-24       Impact factor: 5.422

7.  Investigation of Inter- and Intratumoral Heterogeneity of Glioblastoma Using TOF-SIMS.

Authors:  Samvel K Gularyan; Alexander A Gulin; Ksenia S Anufrieva; Victoria O Shender; Michail I Shakhparonov; Soniya Bastola; Nadezhda V Antipova; Tatiana F Kovalenko; Yury P Rubtsov; Yaroslav A Latyshev; Alexander A Potapov; Marat S Pavlyukov
Journal:  Mol Cell Proteomics       Date:  2020-04-06       Impact factor: 5.911

8.  Enrichment and Characterization of the Tumor Immune and Non-immune Microenvironments in Established Subcutaneous Murine Tumors.

Authors:  Jared M Newton; Aurelie Hanoteau; Andrew G Sikora
Journal:  J Vis Exp       Date:  2018-06-07       Impact factor: 1.355

Review 9.  How to dissect the plasticity of antigen-specific immune response: a tissue perspective.

Authors:  D Amodio; V Santilli; P Zangari; N Cotugno; E C Manno; S Rocca; P Rossi; C Cancrini; A Finocchi; A Chassiakos; C Petrovas; P Palma
Journal:  Clin Exp Immunol       Date:  2019-10-31       Impact factor: 4.330

Review 10.  Comparisons of Underlying Mechanisms, Clinical Efficacy and Safety Between Anti-PD-1 and Anti-PD-L1 Immunotherapy: The State-of-the-Art Review and Future Perspectives.

Authors:  Yating Zhao; Liu Liu; Liang Weng
Journal:  Front Pharmacol       Date:  2021-07-07       Impact factor: 5.810
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