Literature DB >> 2717520

Complex formation between metronidazole and sodium urate: effect on photodegradation of metronidazole.

M J Habib1, A F Asker.   

Abstract

Photodegradation of solutions of metronidazole in the presence and absence of sodium urate was studied. Photodegradation appeared to follow zero-order kinetics and was found to be dependent on the pH, buffer species, sodium urate concentration, and light source. Complex formation between metronidazole and sodium urate accounted for the photostabilization of metronidazole. The dissociation constant for this complex was calculated to be 3.4 x 10(-3) M.

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Year:  1989        PMID： 2717520     DOI： 10.1023/a:1015851719579

Source DB:  PubMed          Journal:  Pharm Res        ISSN： 0724-8741            Impact factor:   4.200


  3 in total

1.  [Reaction of lactoflavin with phenols in aqueous solution].

Authors:  Y MATSUOKA; K YAGI
Journal:  Biochem Z       Date:  1956

Review 2.  Hypoxic sensitizers--implications for radiation therapy.

Authors:  J D Chapman
Journal:  N Engl J Med       Date:  1979-12-27       Impact factor: 91.245

3.  Complex formation between menadione and cetylethylmorpholinium ethosulfate: effect on UV photodegradation of menadione.

Authors:  C R Kowarski; H I Ghandi
Journal:  J Pharm Sci       Date:  1975-04       Impact factor: 3.534
  3 in total
  1 in total

1.  Effective reduction of metronidazole over the cryptomelane-type manganese oxide octahedral molecular sieve (K-OMS-2) catalyst: facile synthesis, experimental design and modeling, statistical analysis, and identification of by-products.

Authors:  Ebrahim Mohammadi Kalhori; Esmaeil Ghahramani; Tariq J Al-Musawi; Hossien Najafi Saleh; Mohammad Noori Sepehr; Mansur Zarrabi
Journal:  Environ Sci Pollut Res Int       Date:  2018-10-04       Impact factor: 4.223
  1 in total

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