Literature DB >> 2717512

Kinetics of drug decomposition by heat conduction calorimetry.

L D Hansen1, E A Lewis, D J Eatough, R G Bergstrom, D DeGraft-Johnson.   

Abstract

The application of heat conduction calorimetry to the determination of decomposition mechanisms and rates for drugs is shown to be a rapid and generally useful method. The application of the method to determine the nature of the decomposition reaction, sources of systematic errors in the method, the equations relating the calorimetric signal to the kinetics of the reaction, and some examples of results are presented and discussed.

Mesh：

Year:  1989        PMID： 2717512     DOI： 10.1023/a:1015851100015

Source DB:  PubMed          Journal:  Pharm Res        ISSN： 0724-8741            Impact factor:   4.200


  9 in total

1.  Prediction of stability of drugs and pharmaceutical preparations.

Authors:  E R GARRETT
Journal:  J Pharm Sci       Date:  1962-09       Impact factor: 3.534

2.  Analysis of drugs by microcalorimetry Isothermal power-conduction calorimetry and thermometric titrimetry.

Authors:  B Z Chowdhry; A E Beezer; E J Greenhow
Journal:  Talanta       Date:  1983-04       Impact factor: 6.057

3.  Direct measurement of the energetics of association between myelin basic protein and phosphatidylserine vesicles.

Authors:  G Ramsay; R Prabhu; E Freire
Journal:  Biochemistry       Date:  1986-04-22       Impact factor: 3.162

Review 4.  A critical appraisal of drug stability testing methods.

Authors:  R B Taylor; A S Shivji
Journal:  Pharm Res       Date:  1987-06       Impact factor: 4.200

5.  Thermochemistry of the interaction between peptides and vancomycin or ristocetin.

Authors:  A Rodríguez-Tebar; D Vázquez; J L Pérez Velázquez; J Laynez; I Wadsö
Journal:  J Antibiot (Tokyo)       Date:  1986-11       Impact factor: 2.649

6.  3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors. 4. Side chain ester derivatives of mevinolin.

Authors:  W F Hoffman; A W Alberts; P S Anderson; J S Chen; R L Smith; A K Willard
Journal:  J Med Chem       Date:  1986-05       Impact factor: 7.446

Review 7.  Stability of solids and solid dosage forms.

Authors:  J T Carstensen
Journal:  J Pharm Sci       Date:  1974-01       Impact factor: 3.534

8.  Analytical chemistry in the drug development process.

Authors:  M J Frank
Journal:  Anal Chem       Date:  1985-01       Impact factor: 6.986

9.  Mevinolin: a highly potent competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase and a cholesterol-lowering agent.

Authors:  A W Alberts; J Chen; G Kuron; V Hunt; J Huff; C Hoffman; J Rothrock; M Lopez; H Joshua; E Harris; A Patchett; R Monaghan; S Currie; E Stapley; G Albers-Schonberg; O Hensens; J Hirshfield; K Hoogsteen; J Liesch; J Springer
Journal:  Proc Natl Acad Sci U S A       Date:  1980-07       Impact factor: 11.205
  9 in total
  3 in total

1.  Solid-state stability testing of drugs by isothermal calorimetry.

Authors:  M J Koenigbauer; S H Brooks; G Rullo; R A Couch
Journal:  Pharm Res       Date:  1992-07       Impact factor: 4.200

2.  A kinetic study on crystallization of an amorphous lubricant.

Authors:  V P Lehto; E Laine
Journal:  Pharm Res       Date:  1997-07       Impact factor: 4.200

Review 3.  Pharmaceutical applications of microcalorimetry.

Authors:  M J Koenigbauer
Journal:  Pharm Res       Date:  1994-06       Impact factor: 4.200
  3 in total

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