Literature DB >> 27174417

Preferences for 'New' Treatments Diminish in the Face of Ambiguity.

Mark Harrison1,2, Carlo A Marra3, Nick Bansback2,4.   

Abstract

New products usually offer advantages over existing products, but in health care, most new drugs are 'me-too', comparable in effectiveness and side effects to existing drugs, but with a more ambiguous evidence base around adverse effects. Despite this, new treatments drive increased health care spending, suggesting a preference for 'newness' in this setting. We explore (1) whether preferences for treatments labeled 'new' exist and (2) persist once the ambiguity in the evidence base reflecting newness is described. We use a Canadian general population sample (n = 2837) characterized by their innovativeness in adopting new products in normal markets. We found that innovators/early adopters (n = 173) had significant preferences for 'newer' treatments (B = 0.162, p = 0.038) irrespective of comparable benefits and side effects and all respondents had significant preferences for less ambiguity in benefit/side effect estimates. Notably, when 'newness' was combined with ambiguity, no significant preferences for new treatments were observed regardless of respondent innovativeness. We conclude that preferences for new products exist for some people in health care markets but disappear when the implication of ambiguity in the evidence base for new treatments is communicated. Physicians should avoid describing treatments as 'new' or be mindful to qualify the implications of 'new' treatments in terms of evidence ambiguity.
Copyright © 2016 John Wiley & Sons, Ltd. Copyright © 2016 John Wiley & Sons, Ltd.

Entities:  

Keywords:  decision-making; diffusion; discrete choice experiments; imprecision; treatment uncertainty

Mesh:

Year:  2016        PMID: 27174417     DOI: 10.1002/hec.3353

Source DB:  PubMed          Journal:  Health Econ        ISSN: 1057-9230            Impact factor:   3.046


  5 in total

1.  Identifying content to improve risk assessment communications within the Risk Profile: Literature reviews and focus groups with expert and non-expert stakeholders.

Authors:  C Ellermann; M McDowell; C O Schirren; A-K Lindemann; S Koch; M Lohmann; M A Jenny
Journal:  PLoS One       Date:  2022-04-11       Impact factor: 3.240

2.  Public perceptions of the association between drug effectiveness and drug novelty in France during the COVID-19 pandemic.

Authors:  Émilien Schultz; Léo Mignot; Jeremy K Ward; Daniela Boaventura Bomfim; Christian Chabannon; Julien Mancini
Journal:  Therapie       Date:  2022-05-07       Impact factor: 3.367

Review 3.  Application of discrete choice experiments to enhance stakeholder engagement as a strategy for advancing implementation: a systematic review.

Authors:  Ramzi G Salloum; Elizabeth A Shenkman; Jordan J Louviere; David A Chambers
Journal:  Implement Sci       Date:  2017-11-23       Impact factor: 7.327

Review 4.  Me-too pharmaceutical products: History, definitions, examples, and relevance to drug shortages and essential medicines lists.

Authors:  Jeffrey K Aronson; A Richard Green
Journal:  Br J Clin Pharmacol       Date:  2020-05-13       Impact factor: 4.335

5.  Determinants of drug expenditure in the Swiss healthcare market in 2006.

Authors:  Yves Eggli; Anne Decollogny; Romain Piaget-Rossel; Patrick Taffé
Journal:  BMC Health Serv Res       Date:  2022-07-07       Impact factor: 2.908

  5 in total

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