Literature DB >> 27172579

Longitudinal Effects of Early Childhood Maltreatment on Co-Occurring Substance Misuse and Mental Health Problems in Adulthood: The Role of Adolescent Alcohol Use and Depression.

Martie L Skinner1, Seunghye Hong2, Todd I Herrenkohl1, Eric C Brown3, Jungeun Olivia Lee4, Hyunzee Jung1.   

Abstract

OBJECTIVE: This study tested a developmental model in which subtypes of childhood maltreatment were hypothesized to have direct and indirect effects on co-occurring depression, anxiety, and substance misuse in adulthood. Indirect effects involved adolescent alcohol use and depression, which were included as mediators in the tested models.
METHOD: This prospective longitudinal study (N = 332; 52.4% male) followed the participants from childhood (18 months to 6 years of age) to adulthood (31-41 years old, M = 36.21). Maltreatment subtypes included parent-reported physical and emotional abuse and child-reported sexual abuse. Adult outcomes included measures of substance misuse and mental health (i.e., depression and anxiety). Latent class analysis and structural equation models were used to identify classes of substance misuse and mental health co-occurrence and to test mediating effects of adolescent alcohol use and depression.
RESULTS: Three classes were identified: (a) low risk of substance misuse and low mental health symptoms, (b) moderate substance misuse risk and mild depression and anxiety, and (c) moderate substance misuse risk and moderate to high depression and anxiety. Structural models showed that effects of childhood sexual abuse were fully mediated by adolescent alcohol use and depression. Physical abuse increased adolescent depression but did not have direct or indirect effects on adult outcome classes. Emotional abuse had a direct effect on the adult classes.
CONCLUSIONS: Children exposed to severe emotional abuse are at higher risk for comorbid substance misuse, depression, and anxiety into their mid-30s, after taking into account evidence of alcohol use and depression during adolescence. Sexual and physical abuse have more proximal effects on adolescent alcohol use and depression, which then influence the risk of adult problems.

Entities:  

Mesh:

Year:  2016        PMID: 27172579      PMCID: PMC4869903          DOI: 10.15288/jsad.2016.77.464

Source DB:  PubMed          Journal:  J Stud Alcohol Drugs        ISSN: 1937-1888            Impact factor:   2.582


  18 in total

1.  Preschool antecedents of adolescent assaultive behavior: a longitudinal study.

Authors:  R C Herrenkohl; B P Egolf; E C Herrenkohl
Journal:  Am J Orthopsychiatry       Date:  1997-07

2.  Structural models of the comorbidity of internalizing disorders and substance use disorders in a longitudinal birth cohort.

Authors:  David M Fergusson; Joseph M Boden; L John Horwood
Journal:  Soc Psychiatry Psychiatr Epidemiol       Date:  2010-07-09       Impact factor: 4.328

3.  Beyond generalized anxiety disorder: psychometric properties of the GAD-7 in a heterogeneous psychiatric sample.

Authors:  C Beard; T Björgvinsson
Journal:  J Anxiety Disord       Date:  2014-06-14

4.  Resilience among abused and neglected children grown up.

Authors:  J M McGloin; C S Widom
Journal:  Dev Psychopathol       Date:  2001

5.  Differences in early childhood risk factors for juvenile-onset and adult-onset depression.

Authors:  Sara R Jaffee; Terrie E Moffitt; Avshalom Caspi; Eric Fombonne; Richie Poulton; Judith Martin
Journal:  Arch Gen Psychiatry       Date:  2002-03

Review 6.  Child maltreatment.

Authors:  Dante Cicchetti; Sheree L Toth
Journal:  Annu Rev Clin Psychol       Date:  2005       Impact factor: 18.561

7.  Childhood trauma and health outcomes in adults with comorbid substance abuse and mental health disorders.

Authors:  Nancy S Wu; Laura C Schairer; Elinam Dellor; Christine Grella
Journal:  Addict Behav       Date:  2009-09-11       Impact factor: 3.913

8.  Revictimization and self-harm in females who experienced childhood sexual abuse: results from a prospective study.

Authors:  Jennie G Noll; Lisa A Horowitz; George A Bonanno; Penelope K Trickett; Frank W Putnam
Journal:  J Interpers Violence       Date:  2003-12

9.  Standardized Beck Depression Inventory-II scores for male veterans coping with chronic pain.

Authors:  Michael N Lopez; Russell S Pierce; Ricca D Gardner; Richard W Hanson
Journal:  Psychol Serv       Date:  2012-09-24

10.  MAOA, maltreatment, and gene-environment interaction predicting children's mental health: new evidence and a meta-analysis.

Authors:  J Kim-Cohen; A Caspi; A Taylor; B Williams; R Newcombe; I W Craig; T E Moffitt
Journal:  Mol Psychiatry       Date:  2006-06-27       Impact factor: 15.992

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  5 in total

Review 1.  The Devastating Clinical Consequences of Child Abuse and Neglect: Increased Disease Vulnerability and Poor Treatment Response in Mood Disorders.

Authors:  Elizabeth T C Lippard; Charles B Nemeroff
Journal:  Am J Psychiatry       Date:  2019-09-20       Impact factor: 18.112

2.  Behavioral, mental, and physical health characteristics and opioid medication misuse among community pharmacy patients: A latent class analysis.

Authors:  Gerald Cochran; Valerie Hruschak; Jennifer L Bacci; Kenneth C Hohmeier; Ralph Tarter
Journal:  Res Social Adm Pharm       Date:  2016-11-15

Review 3.  Early life stress and substance use disorders: The critical role of adolescent substance use.

Authors:  Dylan E Kirsch; Elizabeth T C Lippard
Journal:  Pharmacol Biochem Behav       Date:  2022-02-25       Impact factor: 3.533

4.  Bullying, Psychological, and Physical Trauma During Early Life Increase Risk of Major Depressive Disorder in Adulthood: A Nationwide Community Sample of Korean Adults.

Authors:  Hyun Soo Kim; Hong Jin Pyo; Maurizio Fava; David Mischoulon; Mi Jin Park; Hong Jin Jeon
Journal:  Front Psychiatry       Date:  2022-03-25       Impact factor: 4.157

5.  Patterns of adverse childhood experiences and depressive symptom trajectories in young adults: A longitudinal study of college students in China.

Authors:  Shuqin Li; Rui Wang; Erica Thomas; Zhicheng Jiang; Zhengge Jin; Ruoyu Li; Yan Qian; Xianbing Song; Ying Sun; Shichen Zhang; Ruoling Chen; Yuhui Wan
Journal:  Front Psychiatry       Date:  2022-07-25       Impact factor: 5.435

  5 in total

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