Literature DB >> 27171379

Atypical Fibroxanthoma of the Conjunctiva in Xeroderma Pigmentosum.

Nabeel Shalabi1, Anat Galor2, Sander R Dubovy3, Jordan Thompson4, J Antonio Bermudez-Magner4, Carol L Karp4.   

Abstract

BACKGROUND: Atypical fibroxanthoma (AFX) is a pleomorphic tumor that most commonly presents in the elderly and arises on sun-exposed skin.
METHODS: We report a case of a 24-year-old white male with xeroderma pigmentosum (XP), who developed an AFX of the conjunctiva, and review the literature.
RESULTS: The patient presented with a rapidly growing conjunctival mass which was surgically excised and found to be AFX. The patient has done well with no recurrence. A review of the literature was performed, and we found that only one other case has been published so far.
CONCLUSION: Patients with XP may present with unusual tumors, including nonepithelial soft-tissue tumors. AFX is a rapidly growing tumor which may rarely present on the ocular surface.

Entities:  

Keywords:  Atypical fibroxanthoma; Malignant fibrous histiocytoma; Skin tumor; Xeroderma pigmentosum

Year:  2015        PMID: 27171379      PMCID: PMC4847688          DOI: 10.1159/000377682

Source DB:  PubMed          Journal:  Ocul Oncol Pathol        ISSN: 2296-4657


  16 in total

1.  Immunoexpression of ultraviolet photoproducts and p53 mutation analysis in atypical fibroxanthoma and superficial malignant fibrous histiocytoma.

Authors:  A Sakamoto; Y Oda; E Itakura; Y Oshiro; O Nikaido; Y Iwamoto; M Tsuneyoshi
Journal:  Mod Pathol       Date:  2001-06       Impact factor: 7.842

Review 2.  Ocular surface squamous neoplasia.

Authors:  G A Lee; L W Hirst
Journal:  Surv Ophthalmol       Date:  1995 May-Jun       Impact factor: 6.048

3.  Atypical fibroxanthoma of the skin and the lower lip in xeroderma pigmentosum.

Authors:  F H Dilek; N Akpolat; A Metin; S Ugras
Journal:  Br J Dermatol       Date:  2000-09       Impact factor: 9.302

4.  Atypical fibroxanthoma: a clinicopathological study of 89 cases.

Authors:  Basit Mirza; David Weedon
Journal:  Australas J Dermatol       Date:  2005-11       Impact factor: 2.875

5.  Two unusual tumors in a patient with xeroderma pigmentosum: atypical fibroxanthoma and basosquamous carcinoma.

Authors:  N Youssef; P Vabres; T Buisson; N Brousse; S Fraitag
Journal:  J Cutan Pathol       Date:  1999-10       Impact factor: 1.587

6.  Ultraviolet-induced p53 mutations in atypical fibroxanthoma.

Authors:  A P Dei Tos; R Maestro; C Doglioni; D Gasparotto; M Boiocchi; L Laurino; C D Fletcher
Journal:  Am J Pathol       Date:  1994-07       Impact factor: 4.307

Review 7.  Malignant fibrous histiocytoma of the skin and the conjunctiva in xeroderma pigmentosum.

Authors:  J Pe'er; S Levinger; M Chirambo; N Ron; E Okon
Journal:  Arch Pathol Lab Med       Date:  1991-09       Impact factor: 5.534

8.  Xeroderma pigmentosum. Cutaneous, ocular, and neurologic abnormalities in 830 published cases.

Authors:  K H Kraemer; M M Lee; J Scotto
Journal:  Arch Dermatol       Date:  1987-02

9.  Atypical fibroxanthoma versus benign and malignant fibrous histiocytoma. A comparative study of their proliferative activity using MIB-1, DNA flow cytometry, and p53 immunostaining.

Authors:  Y Oshiro; T Fukuda; M Tsuneyoshi
Journal:  Cancer       Date:  1995-03-01       Impact factor: 6.860

10.  Atypical fibroxanthoma: an unusual skin neoplasm in xeroderma pigmentosum.

Authors:  Ranjana Bandyopadhyay; Dipanwita Nag; Sanjay Bandyopadhyay; Swapan Kumar Sinha
Journal:  Indian J Dermatol       Date:  2012-09       Impact factor: 1.494

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  2 in total

1.  Corneoscleral locally aggressive fibrous histiocytoma in Xeroderma Pigmentosum patient: A case report.

Authors:  Hind M Alkatan; Azza M Y Maktabi
Journal:  Saudi J Ophthalmol       Date:  2017-08-07

2.  Atypical Fibroxanthoma of the Bulbar Conjunctiva: A Unique Case Describing the Pathology, Clinical Presentation, and Management.

Authors:  Justin Kuiper; Ankit Shah; Rebecca Kuennen; Lynn Schoenfield
Journal:  Ocul Oncol Pathol       Date:  2017-10-20
  2 in total

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