Literature DB >> 27171013

Treatment Challenges with Benign Bone Tumors of the Orbit.

Helen Merritt1, Vivian T Yin2, Margaret L Pfeiffer1, Wei-Lien Wang3, Matthew C Sniegowski2, Bita Esmaeli2.   

Abstract

Benign mesenchymal tumors of the craniofacial complex present unique challenges for orbital surgeons because of their potential for orbital compartment syndrome, ocular morbidity, and facial disfigurement and because definitive surgical management may be associated with significant morbidity. While the precise classification of such lesions depends on radiologic as well as histologic evaluations and remains controversial, benign tumors involving the bony walls of the orbit share features of bony expansion, facial deformity, and the potential to cause significant orbital and ophthalmic morbidity. We herein present 2 cases of benign mesenchymal tumors with bony involvement in the orbitofacial region (1 juvenile ossifying fibroma and 1 central giant cell granuloma) and review the current management of similar benign fibro-osseous and reactive bone lesions of the orbit. These rare entities presented share common orbital and ophthalmic manifestations and remain without any effective definitive treatment options.

Entities:  

Keywords:  Central giant cell granuloma; Facial deformity; Fibro-osseous lesions; Juvenile ossifying fibroma; Mesenchymal tumors; Orbital bones; Reactive bone lesions

Year:  2015        PMID: 27171013      PMCID: PMC4847673          DOI: 10.1159/000368651

Source DB:  PubMed          Journal:  Ocul Oncol Pathol        ISSN: 2296-4657


  52 in total

1.  Giant-cell reparative granuloma and related conditions affecting the jawbones.

Authors:  L T AUSTIN; D C DAHLIN; R Q ROYER
Journal:  Oral Surg Oral Med Oral Pathol       Date:  1959-11

2.  Craniofacial resection of ossifying fibromas and osteomas of the sinuses.

Authors:  A Blitzer; K D Post; J Conley
Journal:  Arch Otolaryngol Head Neck Surg       Date:  1989-09

3.  Ossifying fibroma: a clinicopathologic study of sixty-four cases.

Authors:  L R Eversole; A S Leider; K Nelson
Journal:  Oral Surg Oral Med Oral Pathol       Date:  1985-11

4.  Calcitonin therapy in central giant cell granuloma of the jaw: a randomized double-blind placebo-controlled study.

Authors:  J de Lange; H P van den Akker; G O Veldhuijzen van Zanten; H A Engelshove; H van den Berg; H Klip
Journal:  Int J Oral Maxillofac Surg       Date:  2006-07-10       Impact factor: 2.789

5.  Rapid biochemical response to denosumab in fibrous dysplasia of bone: report of two cases.

Authors:  K Ganda; M J Seibel
Journal:  Osteoporos Int       Date:  2013-12-06       Impact factor: 4.507

6.  Immunohistochemical expression of glucocorticoid and calcitonin receptors as a tool for selecting therapeutic approach in central giant cell granuloma of the jawbones.

Authors:  M Vered; A Buchner; D Dayan
Journal:  Int J Oral Maxillofac Surg       Date:  2006-03-31       Impact factor: 2.789

7.  Radical treatment for fronto-orbital fibrous dysplasia: the chain-link fence.

Authors:  I R Munro; Y R Chen
Journal:  Plast Reconstr Surg       Date:  1981-06       Impact factor: 4.730

8.  Targeting receptor-activator of nuclear kappaB ligand in aneurysmal bone cysts: verification of target and therapeutic response.

Authors:  Dominic W Pelle; Jonathan W Ringler; Jacqueline D Peacock; Kevin Kampfschulte; Donald J Scholten; Mary M Davis; Deanna S Mitchell; Matthew R Steensma
Journal:  Transl Res       Date:  2014-03-21       Impact factor: 7.012

9.  Optic nerve decompression in cranial base fibrous dysplasia.

Authors:  F A Papay; L Morales; P Flaharty; S J Smith; R Anderson; J M WAlker; R S Hood; S Hardy
Journal:  J Craniofac Surg       Date:  1995-01       Impact factor: 1.046

10.  Peripheral and central giant cell granulomas of the jaws: a demographic study.

Authors:  Mohammad Hosein Kalantar Motamedi; Nosratollah Eshghyar; Seyyed Mehdi Jafari; Essagh Lassemi; Fina Navi; Fatemeh Mashhadi Abbas; Sam Khalifeh; Pooyan Sadr Eshkevari
Journal:  Oral Surg Oral Med Oral Pathol Oral Radiol Endod       Date:  2007-04-11
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  1 in total

1.  A large maxillary cemento-ossifying fibroma superimposed with solitary bone cyst documented over 18 years: A case report.

Authors:  Sarmad Aburas; Patrick Bandura; Ali Al-Ibraheem; Sebastian Berger; Marius Meier; Dritan Turhani
Journal:  Int J Surg Case Rep       Date:  2020-03-07
  1 in total

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