| Literature DB >> 27170782 |
Mehmet Bozbay1, Huseyin Uyarel2, Gokhan Cicek3, Ahmet Oz1, Muhammed Keskin1, Ahmet Murat1, Ersin Yildirim4, Gurkan Karaca5, Mehmet Ergelen2, Mehmet Eren1.
Abstract
CHA2DS2-VASc score includes similar risk factors for coronary artery disease. We hypothesized that admission CHA2DS2-VASc score might be predictive of adverse clinical outcomes for patients with ST-segment elevation myocardial infarction (STEMI) who were undergoing primary percutaneous coronary intervention. A total of 647 patients with STEMI enrolled in this study. The study population was divided into 2 groups according to their admission CHA2DS2-VASc score. The low group (n = 521) was defined as CHA2DS2-VASc score ≤2, and the high group (n = 126) was defined as CHA2DS2-VASc score >2. Patients in the high group had significantly higher incidence of in-hospital cardiovascular mortality (8.7% vs 1.9%; P < .001). Long-term mortality was significantly frequent in the high group (13.4% vs 3.6%, P < .001). Hypertension, admission CHA2DS2-VASc score, and Killip class >1 were independent predictors of long-term mortality. Admission CHA2DS2-VASc score >2 was identified as an effective cutoff point for long-term mortality (area under curve = 0.821; 95% confidence interval: 0.76-0.89; P < .001). CHA2DS2-VASc score is a simple, very useful, easily remembered bedside score for predicting in-hospital and long-term adverse clinical outcomes in STEMI.Entities:
Keywords: CHA2DS2-VASc score; long-term; mortality; myocardial infarction
Mesh:
Year: 2016 PMID: 27170782 DOI: 10.1177/1076029616646874
Source DB: PubMed Journal: Clin Appl Thromb Hemost ISSN: 1076-0296 Impact factor: 2.389