| Literature DB >> 27170544 |
Lei-Ling Shi1,2, Guo-Xu Ma1,2, Hua-Chun Gao3, Quan-Cheng Chen3, Jun-Shan Yang1, Xiao-Guang Jia2, Jing Zhang4.
Abstract
Five diarylpentanol derivatives including two new compounds stellerasme A (1), stellerasme B (2) were isolated from the aerial parts of Stelleropsis tianschanica. Their structures were elucidated by various spectroscopic techniques (UV, IR, MS, CD, 1D and 2D NMR). All compounds were evaluated for their cytotoxicity activity against HeLa and KB cell lines, and compound 1 showed selective activities against HeLa cell line with an IC50 value of 7.4 μM.Entities:
Keywords: Stelleropsis tianschanica; Thymelaeaceae; cytotoxic activity; diarylpentanol derivatives
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Year: 2016 PMID: 27170544 DOI: 10.1080/10286020.2016.1171759
Source DB: PubMed Journal: J Asian Nat Prod Res ISSN: 1028-6020 Impact factor: 1.569