Literature DB >> 27166040

A sporadic outbreak of Burkholderia cepacia complex bacteremia in pediatric intensive care unit of a tertiary care hospital in coastal Karnataka, South India.

Beena Antony1, Elizabeth Varkey Cherian2, Rekha Boloor1, K Varadraj Shenoy2.   

Abstract

Burkholderia cepacia complex (BCC) is a significant opportunistic pathogen in hospitalized and immunocompromised patients, particularly in cystic fibrosis. It is widely distributed in natural habitats such as soil and water and frequently encountered in nosocomial outbreaks due to contaminated disinfectants and medical devices. However reports on outbreaks due to this organism are lacking from the Indian subcontinent. We report here a sporadic outbreak due to BCC which occurred in the pediatric Intensive Care Unit of our institute, the probable source being contaminated distilled water. The isolate from three babies and environmental sources including distilled water were identical and confirmed as BCC. Strict infection control measures were instituted to prevent the spread of infection. This report highlights the potential role of B.cepacia in causing sporadic outbreaks especially in ICUs, associated with water.

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Year:  2016        PMID: 27166040     DOI: 10.4103/0377-4929.182010

Source DB:  PubMed          Journal:  Indian J Pathol Microbiol        ISSN: 0377-4929            Impact factor:   0.740


  9 in total

Review 1.  Regulation of Virulence by Two-Component Systems in Pathogenic Burkholderia.

Authors:  Matthew M Schaefers
Journal:  Infect Immun       Date:  2020-06-22       Impact factor: 3.441

Review 2.  Burkholderia cepacia Complex Bacteria: a Feared Contamination Risk in Water-Based Pharmaceutical Products.

Authors:  Mariana Tavares; Mariya Kozak; Alexandra Balola; Isabel Sá-Correia
Journal:  Clin Microbiol Rev       Date:  2020-04-15       Impact factor: 26.132

3.  Refractory Burkholderia cepacia bacteraemia from a consolidation pneumonia lasting more than 7 weeks, successfully treated with systemic antibiotics and nebulised meropenem.

Authors:  Bryan Albert Lim; Adelaine Lopez; Joseph Adrian Buensalido
Journal:  BMJ Case Rep       Date:  2019-08-02

4.  Ceftazidime-Resistant Burkholderia Cepacia: An Unusual Case in a Pregnant Patient.

Authors:  Rizwan Ishtiaq; Ali Akram; Laraib Zulfiqar; Daniyal Ishtiaq; Anam Ashraf; Mariam Arif
Journal:  Cureus       Date:  2017-11-01

5.  Infective endocarditis due to Burkholderia cepacia in a neonate: a case report.

Authors:  Emir Yonas; Vito Damay; Raymond Pranata; Nuvi Nusarintowati
Journal:  J Med Case Rep       Date:  2018-05-08

6.  Investigation of Burkholderia cepacia complex bacteremia outbreak in a neonatal intensive care unit: a case series.

Authors:  Tanisha Bharara; Anita Chakravarti; Mukesh Sharma; Priti Agarwal
Journal:  J Med Case Rep       Date:  2020-06-23

Review 7.  Accurate identification and epidemiological characterization of Burkholderia cepacia complex: an update.

Authors:  Naveen Kumar Devanga Ragupathi; Balaji Veeraraghavan
Journal:  Ann Clin Microbiol Antimicrob       Date:  2019-02-04       Impact factor: 3.944

8.  Delayed Pacemaker Generator Pocket and Lead Primary Infection Due to Burkholderia Cepacia.

Authors:  Fatma Ben Abid; Hussam Al-Saoub; Faraj Howadi; Ahmed AlBishawi; Maliha Thapur
Journal:  Am J Case Rep       Date:  2017-08-03

9.  Evolution towards Virulence in a Burkholderia Two-Component System.

Authors:  Matthew M Schaefers; Benjamin X Wang; Nicole M Boisvert; Sarah J Martini; Sarah L Bonney; Christopher W Marshall; Michael T Laub; Vaughn S Cooper; Gregory P Priebe
Journal:  mBio       Date:  2021-08-10       Impact factor: 7.867

  9 in total

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