| Literature DB >> 27165740 |
Abstract
In a recent study, Leucci et al. report a role for the long non-coding RNA SAMMSON in driving mitochondrial function in melanoma. Targeting SAMMSON, the gene of which is frequently co-amplified with MITF, highlights a new cell-type-specific therapeutic vulnerability in melanoma irrespective of BRAF, NRAS, or p53 status.Entities:
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Year: 2016 PMID: 27165740 DOI: 10.1016/j.ccell.2016.04.010
Source DB: PubMed Journal: Cancer Cell ISSN: 1535-6108 Impact factor: 31.743