Literature DB >> 27165739

Coordinated Tumor Suppression by Chromosome 8p.

Darjus F Tschaharganeh1, Benedikt Bosbach1, Scott W Lowe2.   

Abstract

In this issue of Cancer Cell, Cai et al. use genome editing to study 8p deletions in a mammary epithelial cell model and show that 8p loss of heterozygosity (LOH) attenuates the action of several genes that collectively promote cell invasion and enhance cellular sensitivity to autophagy inhibitors.
Copyright © 2016 Elsevier Inc. All rights reserved.

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Year:  2016        PMID： 27165739      PMCID： PMC5120649          DOI： 10.1016/j.ccell.2016.04.011

Source DB:  PubMed          Journal:  Cancer Cell        ISSN： 1535-6108            Impact factor:   31.743


  10 in total

1.  Loss of Chromosome 8p Governs Tumor Progression and Drug Response by Altering Lipid Metabolism.

Authors:  Yanyan Cai; Jonathan Crowther; Tibor Pastor; Layka Abbasi Asbagh; Maria Francesca Baietti; Magdalena De Troyer; Iria Vazquez; Ali Talebi; Fabrizio Renzi; Jonas Dehairs; Johannes V Swinnen; Anna A Sablina
Journal:  Cancer Cell       Date:  2016-05-09       Impact factor: 31.743

2.  PVT1 dependence in cancer with MYC copy-number increase.

Authors:  Yuen-Yi Tseng; Branden S Moriarity; Wuming Gong; Ryutaro Akiyama; Ashutosh Tiwari; Hiroko Kawakami; Peter Ronning; Brian Reuland; Kacey Guenther; Thomas C Beadnell; Jaclyn Essig; George M Otto; M Gerard O'Sullivan; David A Largaespada; Kathryn L Schwertfeger; York Marahrens; Yasuhiko Kawakami; Anindya Bagchi
Journal:  Nature       Date:  2014-06-22       Impact factor: 49.962

3.  Deletions linked to TP53 loss drive cancer through p53-independent mechanisms.

Authors:  Yu Liu; Chong Chen; Zhengmin Xu; Claudio Scuoppo; Cory D Rillahan; Jianjiong Gao; Barbara Spitzer; Benedikt Bosbach; Edward R Kastenhuber; Timour Baslan; Sarah Ackermann; Lihua Cheng; Qingguo Wang; Ting Niu; Nikolaus Schultz; Ross L Levine; Alea A Mills; Scott W Lowe
Journal:  Nature       Date:  2016-03-16       Impact factor: 49.962

4.  p15Ink4b is a critical tumour suppressor in the absence of p16Ink4a.

Authors:  Paul Krimpenfort; Annemieke Ijpenberg; Ji-Ying Song; Martin van der Valk; Martijn Nawijn; John Zevenhoven; Anton Berns
Journal:  Nature       Date:  2007-08-23       Impact factor: 49.962

5.  Cancer vulnerabilities unveiled by genomic loss.

Authors:  Deepak Nijhawan; Travis I Zack; Yin Ren; Matthew R Strickland; Rebecca Lamothe; Steven E Schumacher; Aviad Tsherniak; Henrike C Besche; Joseph Rosenbluh; Shyemaa Shehata; Glenn S Cowley; Barbara A Weir; Alfred L Goldberg; Jill P Mesirov; David E Root; Sangeeta N Bhatia; Rameen Beroukhim; William C Hahn
Journal:  Cell       Date:  2012-08-17       Impact factor: 41.582

6.  A cluster of cooperating tumor-suppressor gene candidates in chromosomal deletions.

Authors:  Wen Xue; Thomas Kitzing; Stephanie Roessler; Johannes Zuber; Alexander Krasnitz; Nikolaus Schultz; Kate Revill; Susann Weissmueller; Amy R Rappaport; Janelle Simon; Jack Zhang; Weijun Luo; James Hicks; Lars Zender; Xin Wei Wang; Scott Powers; Michael Wigler; Scott W Lowe
Journal:  Proc Natl Acad Sci U S A       Date:  2012-05-07       Impact factor: 11.205

7.  Cumulative haploinsufficiency and triplosensitivity drive aneuploidy patterns and shape the cancer genome.

Authors:  Teresa Davoli; Andrew Wei Xu; Kristen E Mengwasser; Laura M Sack; John C Yoon; Peter J Park; Stephen J Elledge
Journal:  Cell       Date:  2013-10-31       Impact factor: 41.582

8.  Recurrent hemizygous deletions in cancers may optimize proliferative potential.

Authors:  Nicole L Solimini; Qikai Xu; Craig H Mermel; Anthony C Liang; Michael R Schlabach; Ji Luo; Anna E Burrows; Anthony N Anselmo; Andrea L Bredemeyer; Mamie Z Li; Rameen Beroukhim; Matthew Meyerson; Stephen J Elledge
Journal:  Science       Date:  2012-05-24       Impact factor: 47.728

9.  A tumour suppressor network relying on the polyamine-hypusine axis.

Authors:  Claudio Scuoppo; Cornelius Miething; Lisa Lindqvist; José Reyes; Cristian Ruse; Iris Appelmann; Seungtai Yoon; Alexander Krasnitz; Julie Teruya-Feldstein; Darryl Pappin; Jerry Pelletier; Scott W Lowe
Journal:  Nature       Date:  2012-07-12       Impact factor: 49.962

10.  Identification and validation of oncogenes in liver cancer using an integrative oncogenomic approach.

Authors:  Lars Zender; Mona S Spector; Wen Xue; Peer Flemming; Carlos Cordon-Cardo; John Silke; Sheung-Tat Fan; John M Luk; Michael Wigler; Gregory J Hannon; David Mu; Robert Lucito; Scott Powers; Scott W Lowe
Journal:  Cell       Date:  2006-06-30       Impact factor: 41.582
  10 in total
  6 in total

1.  Loss of maternal chromosome 11 is a signature event in SDHAF2, SDHD, and VHL-related paragangliomas, but less significant in SDHB-related paragangliomas.

Authors:  Attje S Hoekstra; Erik F Hensen; Ekaterina S Jordanova; Esther Korpershoek; Anouk Na van der Horst-Schrivers; Cees Cornelisse; Eleonora P M Corssmit; Frederik J Hes; Jeroen C Jansen; Henricus P M Kunst; Henri J L M Timmers; Adrian Bateman; Diana Eccles; Judith V M G Bovée; Peter Devilee; Jean-Pierre Bayley
Journal:  Oncotarget       Date:  2017-02-28

2.  Haploinsufficiency networks identify targetable patterns of allelic deficiency in low mutation ovarian cancer.

Authors:  Joe Ryan Delaney; Chandni B Patel; Katelyn McCabe Willis; Mina Haghighiabyaneh; Joshua Axelrod; Isabelle Tancioni; Dan Lu; Jaidev Bapat; Shanique Young; Octavia Cadassou; Alena Bartakova; Parthiv Sheth; Carley Haft; Sandra Hui; Cheryl Saenz; David D Schlaepfer; Olivier Harismendy; Dwayne G Stupack
Journal:  Nat Commun       Date:  2017-02-15       Impact factor: 14.919

3.  Tumor copy number alteration burden is a pan-cancer prognostic factor associated with recurrence and death.

Authors:  Haley Hieronymus; Rajmohan Murali; Amy Tin; Kamlesh Yadav; Wassim Abida; Henrik Moller; Daniel Berney; Howard Scher; Brett Carver; Peter Scardino; Nikolaus Schultz; Barry Taylor; Andrew Vickers; Jack Cuzick; Charles L Sawyers
Journal:  Elife       Date:  2018-09-04       Impact factor: 8.140

Review 4.  Putting p53 in Context.

Authors:  Edward R Kastenhuber; Scott W Lowe
Journal:  Cell       Date:  2017-09-07       Impact factor: 41.582

5.  Single-cell analysis of copy-number alterations in serous ovarian cancer reveals substantial heterogeneity in both low- and high-grade tumors.

Authors:  Manonmani Kumar; Robert R Bowers; Joe R Delaney
Journal:  Cell Cycle       Date:  2020-10-30       Impact factor: 4.534

6.  Deletion of 3p13-14 locus spanning FOXP1 to SHQ1 cooperates with PTEN loss in prostate oncogenesis.

Authors:  Haley Hieronymus; Phillip J Iaquinta; John Wongvipat; Anuradha Gopalan; Rajmohan Murali; Ninghui Mao; Brett S Carver; Charles L Sawyers
Journal:  Nat Commun       Date:  2017-10-20       Impact factor: 14.919
  6 in total

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