| Literature DB >> 27165077 |
M Yu Shkurnikov1,2, E N Knyazev3, K A Fomicheva4, D S Mikhailenko4, K M Nyushko4, E K Saribekyan4, T R Samatov3, B Ya Alekseev4.
Abstract
We analyzed the effect of hemolysis on microRNA profi le of blood plasma. It was found that hemolysis of ~0.05% erythrocytes in a sample signifi cantly affected the concentration of 9 microRNA: hsa-miR-486-5p, hsa-miR-16-5p, hsa-miR-451a, hsa-miR-106a-5p, hsa-miR-17-5p, hsa-miR-93-5p, hsa-miR-20a-5p, hsa-miR-107, and hsa-miR-20b-5p. The effect of hemolysis on plasma content of miR-17 family microRNA was demonstrated.Entities:
Keywords: blood plasma; hemolysis; microRNA; microarray analysis
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Year: 2016 PMID： 27165077 DOI： 10.1007/s10517-016-3300-y
Source DB: PubMed Journal: Bull Exp Biol Med ISSN： 0007-4888 Impact factor: 0.804