Literature DB >> 27164021

Diagnosis of tuberculosis based on the detection of a cocktail of mycobacterial antigen 85B, ESAT-6 and cord factor by immuno-PCR.

Promod K Mehta1, Netrapal Singh2, Renu Dharra2, Bhawna Dahiya2, Suman Sharma2, Abhishek Sheoran3, Krishna B Gupta4, Dhruva Chaudhary5, Neeru Mehta6, Mandira Varma-Basil7.   

Abstract

Attempts were made to enhance the sensitivity of immuno-PCR assay based on the detection of cocktail of mycobacterial antigen 85B (Rv1886c), ESAT-6 (Rv3875) and cord factor (trehalose 6,6'-dimycolate) in pulmonary and extrapulmonary TB patients. Detection of Ag85B was found to be superior to the detection of cocktail in TB patients.
Copyright © 2016 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Antigen 85B; Cord factor; ESAT-6; Immuno-PCR; Tuberculosis

Mesh：

Substances：

Year:  2016        PMID： 27164021     DOI： 10.1016/j.mimet.2016.05.003

Source DB:  PubMed          Journal:  J Microbiol Methods        ISSN： 0167-7012            Impact factor:   2.363


  3 in total

1.  Role of Immuno-Polymerase Chain Reaction (I-PCR) in Resolving Diagnostic Dilemma Between Tuberculoma and Neurocysticercosis: A Case Report.

Authors:  Sonia Ahlawat; Surekha Dabla; Vinay Kumar; Machiavelli Singh; Kiran Bala; Promod K Mehta
Journal:  Am J Case Rep       Date:  2018-05-24

2.  Detection of Mycobacterium tuberculosis purified ESAT-6 (Rv3875) by magnetic bead-coupled gold nanoparticle-based immuno-PCR assay.

Authors:  Netrapal Singh; Bhawna Dahiya; Venkatraman Srinivasan Radhakrishnan; Tulika Prasad; Promod K Mehta
Journal:  Int J Nanomedicine       Date:  2018-12-12

3.  Diagnostics of tuberculosis and differentiation of nonspecific tuberculin reactions in animals.

Authors:  Sovetzhan Z Basybekov; Marat B Bazarbayev; Bolat A Yespembetov; Assiya Mussaeva; Serik G Kanatbayev; Kanapya M Romashev; Aigul K Dossanova; Tokseiit A Yelekeyev; Elmira K Akmatova; Nazym S Syrym
Journal:  Braz J Microbiol       Date:  2017-10-25       Impact factor: 2.476
  3 in total

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