Literature DB >> 27160166

The Treatment of Behavioral and Psychological Symptoms of Dementia: Weighing Benefits and Risks.

Kristina F Zdanys1, André F Carvalho, Rajesh R Tampi, David C Steffens.   

Abstract

Behavioral and psychological symptoms of dementia (BPSD) are common among patients with dementia. BPSD have significant implications on outcomes for patients and caregivers. Available literature for pharmacological approaches to BPSD is sparse and at times inconsistent. There are no FDA-approved medications for the management of BPSD, and the use of available medications is associated with significant adverse effects among aged populations with dementia. This review outlines the assessment of BPSD, discusses general principles of management, and examines current evidence for non-pharmacologic and pharmacologic treatment strategies as well as associated risks.

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Year:  2016        PMID： 27160166     DOI： 10.2174/1567205013666160510121633

Source DB:  PubMed          Journal:  Curr Alzheimer Res        ISSN： 1567-2050            Impact factor:   3.498


  6 in total

Review 1.  Serotonergic system, cognition, and BPSD in Alzheimer's disease.

Authors:  Saikat Chakraborty; Jack C Lennon; Sridhar A Malkaram; Yan Zeng; Daniel W Fisher; Hongxin Dong
Journal:  Neurosci Lett       Date:  2019-04-01       Impact factor: 3.046

2.  Blood DNA Methylation Levels in the WNT5A Gene Promoter Region: A Potential Biomarker for Agitation in Subjects with Dementia.

Authors:  Nobuyuki Kobayashi; Shunichiro Shinagawa; Tomoyuki Nagata; Kenji Tagai; Kazuya Shimada; Azusa Ishii; Naomi Oka; Masahiro Shigeta; Kazuhiro Kondo
Journal:  J Alzheimers Dis       Date:  2021       Impact factor: 4.472

Review 3.  Behavioral, Psychiatric, and Cognitive Adverse Events in Older Persons Treated with Glucocorticoids.

Authors:  Ciro Manzo; Jordi Serra-Mestres; Alberto Castagna; Marco Isetta
Journal:  Medicines (Basel)       Date:  2018-08-01

4.  Nursing home care for people with dementia: Update of the design of the Living Arrangements for people with Dementia (LAD)-study.

Authors:  Marleen Prins; Bernadette M Willemse; Ceciel H Heijkants; Anne Margriet Pot
Journal:  J Adv Nurs       Date:  2019-10-20       Impact factor: 3.187

Review 5.  Safety, tolerability, and risks associated with first- and second-generation antipsychotics: a state-of-the-art clinical review.

Authors:  Marco Solmi; Andrea Murru; Isabella Pacchiarotti; Juan Undurraga; Nicola Veronese; Michele Fornaro; Brendon Stubbs; Francesco Monaco; Eduard Vieta; Mary V Seeman; Christoph U Correll; André F Carvalho
Journal:  Ther Clin Risk Manag       Date:  2017-06-29       Impact factor: 2.423

6.  Impact of agitation in long-term care residents with dementia in the United States.

Authors:  Howard Fillit; Myrlene S Aigbogun; Patrick Gagnon-Sanschagrin; Martin Cloutier; Mikhaïl Davidson; Elizabeth Serra; Annie Guérin; Ross A Baker; Christy R Houle; George Grossberg
Journal:  Int J Geriatr Psychiatry       Date:  2021-08-27       Impact factor: 3.850
  6 in total

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