A dual-site two-photon fluorescent probe for visualizing lysosomes and tracking lysosomal hydrogen sulfide with two different sets of fluorescence signals in the living cells and mouse liver tissues.

Herein, we have developed a novel dual-site two-photon fluorescent probe as the first paradigm of the probes, which can concurrently report lysosomes and lysosomal H2S with two different sets of fluorescence signals in the living cells and tissues.