Literature DB >> 27158682

IDH1 Mutations in Glioma: Considerations for Radiotracer Development.

Satish K Chitneni1.   

Abstract

Entities:  

Year:  2016        PMID： 27158682      PMCID： PMC4857886     

Source DB:  PubMed          Journal:  SM Radiol J


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  6 in total

1.  Discovery of the First Potent Inhibitors of Mutant IDH1 That Lower Tumor 2-HG in Vivo.

Authors:  Janeta Popovici-Muller; Jeffrey O Saunders; Francesco G Salituro; Jeremy M Travins; Shunqi Yan; Fang Zhao; Stefan Gross; Lenny Dang; Katharine E Yen; Hua Yang; Kimberly S Straley; Shengfang Jin; Kaiko Kunii; Valeria R Fantin; Shunan Zhang; Qiongqun Pan; Derek Shi; Scott A Biller; Shinsan M Su
Journal:  ACS Med Chem Lett       Date:  2012-09-17       Impact factor: 4.345

2.  Cancer-associated IDH1 mutations produce 2-hydroxyglutarate.

Authors:  Lenny Dang; David W White; Stefan Gross; Bryson D Bennett; Mark A Bittinger; Edward M Driggers; Valeria R Fantin; Hyun Gyung Jang; Shengfang Jin; Marie C Keenan; Kevin M Marks; Robert M Prins; Patrick S Ward; Katharine E Yen; Linda M Liau; Joshua D Rabinowitz; Lewis C Cantley; Craig B Thompson; Matthew G Vander Heiden; Shinsan M Su
Journal:  Nature       Date:  2009-12-10       Impact factor: 49.962

3.  D-2-hydroxyglutarate produced by mutant IDH1 perturbs collagen maturation and basement membrane function.

Authors:  Masato Sasaki; Christiane B Knobbe; Momoe Itsumi; Andrew J Elia; Isaac S Harris; Iok In Christine Chio; Rob A Cairns; Susan McCracken; Andrew Wakeham; Jillian Haight; Annick You Ten; Bryan Snow; Takeshi Ueda; Satoshi Inoue; Kazuo Yamamoto; Myunggon Ko; Anjana Rao; Katharine E Yen; Shinsan M Su; Tak Wah Mak
Journal:  Genes Dev       Date:  2012-08-27       Impact factor: 11.361

4.  Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases.

Authors:  Wei Xu; Hui Yang; Ying Liu; Ying Yang; Ping Wang; Se-Hee Kim; Shinsuke Ito; Chen Yang; Pu Wang; Meng-Tao Xiao; Li-xia Liu; Wen-qing Jiang; Jing Liu; Jin-ye Zhang; Bin Wang; Stephen Frye; Yi Zhang; Yan-hui Xu; Qun-ying Lei; Kun-Liang Guan; Shi-min Zhao; Yue Xiong
Journal:  Cancer Cell       Date:  2011-01-18       Impact factor: 38.585

5.  Selective inhibition of mutant isocitrate dehydrogenase 1 (IDH1) via disruption of a metal binding network by an allosteric small molecule.

Authors:  Gejing Deng; Junqing Shen; Ming Yin; Jessica McManus; Magali Mathieu; Patricia Gee; Timothy He; Chaomei Shi; Olivier Bedel; Larry R McLean; Frank Le-Strat; Ying Zhang; Jean-Pierre Marquette; Qiang Gao; Bailin Zhang; Alexey Rak; Dietmar Hoffmann; Eamonn Rooney; Aurelie Vassort; Walter Englaro; Yi Li; Vinod Patel; Francisco Adrian; Stefan Gross; Dmitri Wiederschain; Hong Cheng; Stuart Licht
Journal:  J Biol Chem       Date:  2014-11-12       Impact factor: 5.486

6.  IDH1 and IDH2 mutations in gliomas.

Authors:  Hai Yan; D Williams Parsons; Genglin Jin; Roger McLendon; B Ahmed Rasheed; Weishi Yuan; Ivan Kos; Ines Batinic-Haberle; Siân Jones; Gregory J Riggins; Henry Friedman; Allan Friedman; David Reardon; James Herndon; Kenneth W Kinzler; Victor E Velculescu; Bert Vogelstein; Darell D Bigner
Journal:  N Engl J Med       Date:  2009-02-19       Impact factor: 176.079
  6 in total
  1 in total

1.  Synthesis and evaluation of radiolabeled AGI-5198 analogues as candidate radiotracers for imaging mutant IDH1 expression in tumors.

Authors:  Satish K Chitneni; Zachary J Reitman; Rebecca Spicehandler; David M Gooden; Hai Yan; Michael R Zalutsky
Journal:  Bioorg Med Chem Lett       Date:  2018-01-12       Impact factor: 2.823
  1 in total

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