Value of 18-Fluoro-2-Deoxyglucose PET in the Management of Patients with Fever of Unknown Origin.

Timely identification of the cause of fever of unknown origin (FUO) is crucial for patient management. The initial evaluation for FUO includes a thorough history, physical examination, and standard laboratory and imaging tests. Advanced diagnostic imaging modalities, such as CT, MRI, and standard nuclear medicine procedures, are commonly used for the assessment of these patients. This article reviews different diagnostic imaging studies that are currently used for examining patients with FUO but also focuses on the role of 18-fluoro-2-deoxyglucose positron emission tomography and its impact on the management of patients with FUO.