Evaluation of Musculoskeletal Disorders with PET, PET/CT, and PET/MR Imaging.

18F-2-fluoro-2-deoxy-D-glucose-PET has an established role in the evaluation of hip periprosthetic infection and musculoskeletal malignancies. Determination of its role in the management of inflammatory arthritis and diabetic foot complications is ongoing. The reintroduction of fluorine F 18 sodium fluoride as a PET radiotracer may advantageously replace technetium Tc 99 m methylene diphosphonate for some non-oncologic applications, including treatment monitoring of Paget's disease andfibrous dysplasia. The combination of CT or MR imaging with PET imaging synergistically maximizes the diagnostic potential of a combined structural-functional imaging approach for the detection, characterization, and monitoring of myriad musculoskeletal disorders. Published by Elsevier Inc.