Literature DB >> 27155227

In vitro selection and amplification protocols for isolation of aptameric sensors for small molecules.

Kyung-Ae Yang1, Renjun Pei2, Milan N Stojanovic3.   

Abstract

We recently optimized a procedure that directly yields aptameric sensors for small molecules in so-called structure-switching format. The protocol has a high success rate, short time, and is sufficiently simple to be readily implemented in a non-specialist laboratory. We provide a stepwise guide to this selection protocol.
Copyright © 2016 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Aptamer; Biosensor; SELEX; Small molecules; Structure-switching

Mesh:

Substances:

Year:  2016        PMID: 27155227      PMCID: PMC4981533          DOI: 10.1016/j.ymeth.2016.04.032

Source DB:  PubMed          Journal:  Methods        ISSN: 1046-2023            Impact factor:   3.608


  8 in total

1.  Optimizing cross-reactivity with evolutionary search for sensors.

Authors:  Kyung-Ae Yang; Renjun Pei; Darko Stefanovic; Milan N Stojanovic
Journal:  J Am Chem Soc       Date:  2012-01-10       Impact factor: 15.419

2.  In vitro selection of structure-switching signaling aptamers.

Authors:  Razvan Nutiu; Yingfu Li
Journal:  Angew Chem Int Ed Engl       Date:  2005-02-04       Impact factor: 15.336

3.  Selection of fluorescent aptamer beacons that light up in the presence of zinc.

Authors:  Manjula Rajendran; Andrew D Ellington
Journal:  Anal Bioanal Chem       Date:  2007-11-30       Impact factor: 4.142

Review 4.  Current approaches in SELEX: An update to aptamer selection technology.

Authors:  Mariia Darmostuk; Silvie Rimpelova; Helena Gbelcova; Tomas Ruml
Journal:  Biotechnol Adv       Date:  2015-02-20       Impact factor: 14.227

5.  A simple and rapid approach for measurement of dissociation constants of DNA aptamers against proteins and small molecules via automated microchip electrophoresis.

Authors:  Jiaming Hu; Christopher J Easley
Journal:  Analyst       Date:  2011-02-03       Impact factor: 4.616

6.  MicroRNA-423-5p Promotes Autophagy in Cancer Cells and Is Increased in Serum From Hepatocarcinoma Patients Treated With Sorafenib.

Authors:  Paola Stiuso; Nicoletta Potenza; Angela Lombardi; Ida Ferrandino; Antonio Monaco; Silvia Zappavigna; Daniela Vanacore; Nicola Mosca; Filomena Castiello; Stefania Porto; Raffaele Addeo; Salvatore Del Prete; Ferdinando De Vita; Aniello Russo; Michele Caraglia
Journal:  Mol Ther Nucleic Acids       Date:  2015-03-17       Impact factor: 10.183

7.  Recognition and sensing of low-epitope targets via ternary complexes with oligonucleotides and synthetic receptors.

Authors:  Kyung-Ae Yang; Mihaela Barbu; Marlin Halim; Payal Pallavi; Benjamin Kim; Dmitry M Kolpashchikov; Stevan Pecic; Steven Taylor; Tilla S Worgall; Milan N Stojanovic
Journal:  Nat Chem       Date:  2014-09-28       Impact factor: 24.427

Review 8.  A Highlight of Recent Advances in Aptamer Technology and Its Application.

Authors:  Hongguang Sun; Youli Zu
Journal:  Molecules       Date:  2015-06-30       Impact factor: 4.411

  8 in total
  20 in total

1.  Electrochemical Aptamer-Based Sensors for Improved Therapeutic Drug Monitoring and High-Precision, Feedback-Controlled Drug Delivery.

Authors:  Philippe Dauphin-Ducharme; Kyungae Yang; Netzahualcóyotl Arroyo-Currás; Kyle L Ploense; Yameng Zhang; Julian Gerson; Martin Kurnik; Tod E Kippin; Milan N Stojanovic; Kevin W Plaxco
Journal:  ACS Sens       Date:  2019-10-15       Impact factor: 7.711

2.  Accelerating Post-SELEX Aptamer Engineering Using Exonuclease Digestion.

Authors:  Juan Canoura; Haixiang Yu; Obtin Alkhamis; Daniel Roncancio; Rifat Farhana; Yi Xiao
Journal:  J Am Chem Soc       Date:  2020-12-30       Impact factor: 15.419

3.  In vitro isolation of class-specific oligonucleotide-based small-molecule receptors.

Authors:  Weijuan Yang; Haixiang Yu; Obtin Alkhamis; Yingzhu Liu; Juan Canoura; Fengfu Fu; Yi Xiao
Journal:  Nucleic Acids Res       Date:  2019-07-09       Impact factor: 16.971

4.  Isolation of Natural DNA Aptamers for Challenging Small-Molecule Targets, Cannabinoids.

Authors:  Haixiang Yu; Yingping Luo; Obtin Alkhamis; Juan Canoura; Boyang Yu; Yi Xiao
Journal:  Anal Chem       Date:  2021-02-02       Impact factor: 6.986

5.  Phenylalanine Monitoring via Aptamer-Field-Effect Transistor Sensors.

Authors:  Kevin M Cheung; Kyung-Ae Yang; Nako Nakatsuka; Chuanzhen Zhao; Mao Ye; Michael E Jung; Hongyan Yang; Paul S Weiss; Milan N Stojanović; Anne M Andrews
Journal:  ACS Sens       Date:  2019-11-01       Impact factor: 7.711

Review 6.  Advances and Challenges in Small-Molecule DNA Aptamer Isolation, Characterization, and Sensor Development.

Authors:  Haixiang Yu; Obtin Alkhamis; Juan Canoura; Yingzhu Liu; Yi Xiao
Journal:  Angew Chem Int Ed Engl       Date:  2021-02-09       Impact factor: 15.336

7.  Phthalic Acid Ester-Binding DNA Aptamer Selection, Characterization, and Application to an Electrochemical Aptasensor.

Authors:  Xiao Wu; Donglin Diao; Zhangwei Lu; Yu Han; Shi Xu; Xinhui Lou
Journal:  J Vis Exp       Date:  2018-03-21       Impact factor: 1.355

8.  Sensing serotonin secreted from human serotonergic neurons using aptamer-modified nanopipettes.

Authors:  Fred H Gage; Krishna C Vadodaria; Nako Nakatsuka; Kelly J Heard; Alix Faillétaz; Dmitry Momotenko; János Vörös
Journal:  Mol Psychiatry       Date:  2021-03-25       Impact factor: 15.992

Review 9.  Aptamers for DNA Damage and Repair.

Authors:  Maureen McKeague
Journal:  Int J Mol Sci       Date:  2017-10-22       Impact factor: 5.923

Review 10.  Aptamer selection and applications for breast cancer diagnostics and therapy.

Authors:  Mei Liu; Xiaocheng Yu; Zhu Chen; Tong Yang; Dandan Yang; Qianqian Liu; Keke Du; Bo Li; Zhifei Wang; Song Li; Yan Deng; Nongyue He
Journal:  J Nanobiotechnology       Date:  2017-11-13       Impact factor: 10.435

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