| Literature DB >> 27155227 |
Kyung-Ae Yang1, Renjun Pei2, Milan N Stojanovic3.
Abstract
We recently optimized a procedure that directly yields aptameric sensors for small molecules in so-called structure-switching format. The protocol has a high success rate, short time, and is sufficiently simple to be readily implemented in a non-specialist laboratory. We provide a stepwise guide to this selection protocol.Entities:
Keywords: Aptamer; Biosensor; SELEX; Small molecules; Structure-switching
Mesh:
Substances:
Year: 2016 PMID: 27155227 PMCID: PMC4981533 DOI: 10.1016/j.ymeth.2016.04.032
Source DB: PubMed Journal: Methods ISSN: 1046-2023 Impact factor: 3.608