| Literature DB >> 27152664 |
Yuelian Sun, Peter Vedsted, Morten Fenger-Grøn, Chun Sen Wu, Bodil Hammer Bech, Jørn Olsen, Michael Eriksen Benros, Mogens Vestergaard.
Abstract
[This corrects the article DOI: 10.1371/journal.pone.0138134.].Entities:
Year: 2016 PMID: 27152664 PMCID: PMC4859561 DOI: 10.1371/journal.pone.0155453
Source DB: PubMed Journal: PLoS One ISSN: 1932-6203 Impact factor: 3.240
Mortality rate ratio (MRR) of cancer mortality after cancer diagnosis for current antidepressant (AD) user and former AD user at time of cancer diagnosis.
| AD treatment before diagnosis | Population | Person years (PYs) | No. of deaths | Mortality/ 100 PYs | Crude MRR | Adjusted | Adjusted |
|---|---|---|---|---|---|---|---|
| 1-year mortality | |||||||
| No | 168,551 | 130,809 | 43,631 | 33.4 | Ref | Ref | Ref |
| Current user | 21,851 | 14,503 | 8,744 | 60.3 | 1.75 | 1.31 (1.28; 1.34) | 1.32 (1.29; 1.35) |
| Former user | 11,260 | 8,374 | 3,396 | 40.6 | 1.21 | 1.05 (1.01; 1.08) | 1.07 (1.03; 1.11) |
| Conditional 5-year mortality if patients survived the first year after cancer diagnosis | |||||||
| No | 105,458 | 236,283 | 23,799 | 10.1 | Ref | Ref | Ref |
| Current user | 10,767 | 22,131 | 3,172 | 14.3 | 1.40 | 1.19 (1.15; 1.24) | 1.22 (1.17; 1.26) |
| Former user | 6,610 | 14,646 | 1,621 | 11.1 | 1.10 | 1.02 (0.97; 1.08) | 1.05 (1.00; 1.11) |
a Current AD users refers to cancer patients who redeemed an AD prescription within 4 months before the cancer diagnosis.
b Former AD users refers to cancer patients who redeemed the last AD prescription more than 4 months before the cancer diagnosis.
c Adjusted for sex, age at time of diagnosis (5-year interval), Charlson comorbidity index (0, 1–2, 3+), marital status (married or cohabiting, living alone), education (low, medium, high), and calendar year (2003–2004, 2005–2007, 2008–2010).
d Adjusted for cancer stage at time of diagnosis (local, regional, distant, and unknown) besides the factors included in the analysis c.
e The reference refers to cancer patients who had no AD prescription in the 3 years before cancer diagnosis.