Literature DB >> 27152442

Induced Pluripotent Stem Cells Meet Genome Editing.

Dirk Hockemeyer1, Rudolf Jaenisch2.   

Abstract

It is extremely rare for a single experiment to be so impactful and timely that it shapes and forecasts the experiments of the next decade. Here, we review how two such experiments-the generation of human induced pluripotent stem cells (iPSCs) and the development of CRISPR/Cas9 technology-have fundamentally reshaped our approach to biomedical research, stem cell biology, and human genetics. We will also highlight the previous knowledge that iPSC and CRISPR/Cas9 technologies were built on as this groundwork demonstrated the need for solutions and the benefits that these technologies provided and set the stage for their success.
Copyright © 2016 Elsevier Inc. All rights reserved.

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Year:  2016        PMID： 27152442      PMCID： PMC4871596          DOI： 10.1016/j.stem.2016.04.013

Source DB:  PubMed          Journal:  Cell Stem Cell        ISSN： 1875-9777            Impact factor:   24.633


  188 in total

1.  Highly efficient endogenous human gene correction using designed zinc-finger nucleases.

Authors:  Fyodor D Urnov; Jeffrey C Miller; Ya-Li Lee; Christian M Beausejour; Jeremy M Rock; Sheldon Augustus; Andrew C Jamieson; Matthew H Porteus; Philip D Gregory; Michael C Holmes
Journal:  Nature       Date:  2005-04-03       Impact factor: 49.962

2.  Single-cell expression analyses during cellular reprogramming reveal an early stochastic and a late hierarchic phase.

Authors:  Yosef Buganim; Dina A Faddah; Albert W Cheng; Elena Itskovich; Styliani Markoulaki; Kibibi Ganz; Sandy L Klemm; Alexander van Oudenaarden; Rudolf Jaenisch
Journal:  Cell       Date:  2012-09-14       Impact factor: 41.582

3.  Sheep cloned by nuclear transfer from a cultured cell line.

Authors:  K H Campbell; J McWhir; W A Ritchie; I Wilmut
Journal:  Nature       Date:  1996-03-07       Impact factor: 49.962

4.  Generation of germline-competent induced pluripotent stem cells.

Authors:  Keisuke Okita; Tomoko Ichisaka; Shinya Yamanaka
Journal:  Nature       Date:  2007-06-06       Impact factor: 49.962

5.  Gene editing of CCR5 in autologous CD4 T cells of persons infected with HIV.

Authors:  Pablo Tebas; David Stein; Winson W Tang; Ian Frank; Shelley Q Wang; Gary Lee; S Kaye Spratt; Richard T Surosky; Martin A Giedlin; Geoff Nichol; Michael C Holmes; Philip D Gregory; Dale G Ando; Michael Kalos; Ronald G Collman; Gwendolyn Binder-Scholl; Gabriela Plesa; Wei-Ting Hwang; Bruce L Levine; Carl H June
Journal:  N Engl J Med       Date:  2014-03-06       Impact factor: 91.245

6.  Cancer-associated TERT promoter mutations abrogate telomerase silencing.

Authors:  Kunitoshi Chiba; Joshua Z Johnson; Jacob M Vogan; Tina Wagner; John M Boyle; Dirk Hockemeyer
Journal:  Elife       Date:  2015-07-21       Impact factor: 8.140

7.  Genetic background drives transcriptional variation in human induced pluripotent stem cells.

Authors:  Foad Rouhani; Natsuhiko Kumasaka; Miguel Cardoso de Brito; Allan Bradley; Ludovic Vallier; Daniel Gaffney
Journal:  PLoS Genet       Date:  2014-06-05       Impact factor: 5.917

8.  Heterodimeric DNA methyltransferases as a platform for creating designer zinc finger methyltransferases for targeted DNA methylation in cells.

Authors:  Glenna E Meister; Srinivasan Chandrasegaran; Marc Ostermeier
Journal:  Nucleic Acids Res       Date:  2009-12-09       Impact factor: 16.971

9.  Targeted DNA demethylation and activation of endogenous genes using programmable TALE-TET1 fusion proteins.

Authors:  Morgan L Maeder; James F Angstman; Marcy E Richardson; Samantha J Linder; Vincent M Cascio; Shengdar Q Tsai; Quan H Ho; Jeffry D Sander; Deepak Reyon; Bradley E Bernstein; Joseph F Costello; Miles F Wilkinson; J Keith Joung
Journal:  Nat Biotechnol       Date:  2013-10-09       Impact factor: 54.908

10.  piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells.

Authors:  Knut Woltjen; Iacovos P Michael; Paria Mohseni; Ridham Desai; Maria Mileikovsky; Riikka Hämäläinen; Rebecca Cowling; Wei Wang; Pentao Liu; Marina Gertsenstein; Keisuke Kaji; Hoon-Ki Sung; Andras Nagy
Journal:  Nature       Date:  2009-03-01       Impact factor: 49.962
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  169 in total

Review 1.  Manufacturing Cell Therapies Using Engineered Biomaterials.

Authors:  Amr A Abdeen; Krishanu Saha
Journal:  Trends Biotechnol       Date:  2017-07-12       Impact factor: 19.536

Review 2.  Telomerase Mechanism of Telomere Synthesis.

Authors:  R Alex Wu; Heather E Upton; Jacob M Vogan; Kathleen Collins
Journal:  Annu Rev Biochem       Date:  2017-01-30       Impact factor: 23.643

3.  Simultaneous reprogramming and gene editing of human fibroblasts.

Authors:  Sara E Howden; James A Thomson; Melissa H Little
Journal:  Nat Protoc       Date:  2018-04-05       Impact factor: 13.491

Review 4.  Pluripotent stem cell-based therapy for Parkinson's disease: Current status and future prospects.

Authors:  Kai-C Sonntag; Bin Song; Nayeon Lee; Jin Hyuk Jung; Young Cha; Pierre Leblanc; Carolyn Neff; Sek Won Kong; Bob S Carter; Jeffrey Schweitzer; Kwang-Soo Kim
Journal:  Prog Neurobiol       Date:  2018-04-11       Impact factor: 11.685

5.  Cardiac Cell Cycle Activation as a Strategy to Improve iPSC-Derived Cardiomyocyte Therapy.

Authors:  June-Wha Rhee; Joseph C Wu
Journal:  Circ Res       Date:  2018-01-05       Impact factor: 17.367

6.  In vivo generated hematopoietic stem cells from genome edited induced pluripotent stem cells are functional in platelet-targeted gene therapy of murine hemophilia A.

Authors:  Dawei Wang; Guowei Zhang; Junjie Gu; Xiaohu Shao; Yuting Dai; Jianfeng Li; Xiaohong Pan; Shuxian Yao; Aining Xu; Ying Jin; Jinyan Huang; Qizhen Shi; Jiang Zhu; Xiaodong Xi; Zhu Chen; Saijuan Chen
Journal:  Haematologica       Date:  2019-07-11       Impact factor: 9.941

Review 7.  New frontiers in modeling tuberous sclerosis with human stem cell-derived neurons and brain organoids.

Authors:  John D Blair; Helen S Bateup
Journal:  Dev Dyn       Date:  2019-05-23       Impact factor: 3.780

Review 8.  Next-generation stem cells - ushering in a new era of cell-based therapies.

Authors:  Erin A Kimbrel; Robert Lanza
Journal:  Nat Rev Drug Discov       Date:  2020-04-06       Impact factor: 84.694

9.  GFAP Mutations in Astrocytes Impair Oligodendrocyte Progenitor Proliferation and Myelination in an hiPSC Model of Alexander Disease.

Authors:  Li Li; E Tian; Xianwei Chen; Jianfei Chao; Jeremy Klein; Qiuhao Qu; Guihua Sun; Guoqiang Sun; Yanzhou Huang; Charles D Warden; Peng Ye; Lizhao Feng; Xinqiang Li; Qi Cui; Abdullah Sultan; Panagiotis Douvaras; Valentina Fossati; Neville E Sanjana; Arthur D Riggs; Yanhong Shi
Journal:  Cell Stem Cell       Date:  2018-08-02       Impact factor: 24.633

10.  Highly Efficient CRISPR-Cas9-Mediated Genome Editing in Human Pluripotent Stem Cells.

Authors:  Jean Ann Maguire; Fabian L Cardenas-Diaz; Paul Gadue; Deborah L French
Journal:  Curr Protoc Stem Cell Biol       Date:  2018-10-24
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