Literature DB >> 27152263

Inflammation and nutrition in children with chronic kidney disease.

Juan Tu1, Wai W Cheung1, Robert H Mak1.   

Abstract

Chronic inflammation and nutritional imbalance are important comorbid conditions that correlate with poor clinical outcomes in children with chronic kidney disease (CKD). Nutritional disorders such as cachexia/protein energy wasting, obesity and growth retardation negatively impact the quality of life and disease progression in children with CKD. Inadequate nutrition has been associated with growth disturbances in children with CKD. On the other hand, over-nutrition and obesity are associated with poor outcomes in children with CKD. The exact mechanisms leading to these unfavorable conditions are not fully elucidated and are most likely multifactorial. In this review, we focus on the pathophysiology of nutrition disorders and inflammation and their impact on clinical outcomes in children with CKD.

Entities:  

Keywords:  Cachexia; Chronic kidney disease; Growth failure; Inflammation; Maternal nutrition; Nutrition; Obesity; Protein energy wasting

Year:  2016        PMID： 27152263      PMCID： PMC4848150          DOI： 10.5527/wjn.v5.i3.274

Source DB:  PubMed          Journal:  World J Nephrol        ISSN： 2220-6124


  68 in total

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3.  Tumor necrosis factor-alpha is associated with mineral bone disorder and growth impairment in children with chronic kidney disease.

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Review 5.  The Impact of Insulin Resistance and Chronic Kidney Disease on Inflammation and Cardiovascular Disease.

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  6 in total

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