| Literature DB >> 27150533 |
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Abstract
The FDA has approved cabozantinib, a tyrosine kinase inhibitor, for patients with advanced renal cell carcinoma who have received prior antiangiogenic therapy. In a randomized phase III trial, participants who received cabozantinib did better across three efficacy endpoints-progression-free survival, overall survival, and objective response rate-than those given the mTOR inhibitor everolimus. ©2016 American Association for Cancer Research.Entities:
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Year: 2016 PMID: 27150533 DOI: 10.1158/2159-8290.CD-NB2016-057
Source DB: PubMed Journal: Cancer Discov ISSN: 2159-8274 Impact factor: 39.397