| Literature DB >> 27150088 |
Yogesh Bhattarai1, Purna C Kashyap2.
Abstract
Germ-free (GF) mice are a relevant model system to study host-microbial interactions in health and disease. In this chapter, we underscore the importance of using GF mice model to study host-microbial interactions in obesity, immune development and gastrointestinal physiology by reviewing current literature. Furthermore, we also provide a brief protocol on how to setup a gnotobiotic facility in order to properly maintain and assess GF status in mice colonies.Entities:
Keywords: Germ-free; Gnotobiotic; Gut microbiome
Mesh:
Year: 2016 PMID: 27150088 DOI: 10.1007/978-1-4939-3661-8_8
Source DB: PubMed Journal: Methods Mol Biol ISSN: 1064-3745