Literature DB >> 27149212

Foretelling toxicity: FDA researchers work to predict risk of liver injury from drugs.

Cassandra Willyard.   

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Year:  2016        PMID: 27149212     DOI: 10.1038/nm0516-450

Source DB:  PubMed          Journal:  Nat Med        ISSN: 1078-8956            Impact factor:   53.440


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  4 in total

Review 1.  DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.

Authors:  Minjun Chen; Ayako Suzuki; Shraddha Thakkar; Ke Yu; Chuchu Hu; Weida Tong
Journal:  Drug Discov Today       Date:  2016-03-03       Impact factor: 7.851

2.  FDA-approved drug labeling for the study of drug-induced liver injury.

Authors:  Minjun Chen; Vikrant Vijay; Qiang Shi; Zhichao Liu; Hong Fang; Weida Tong
Journal:  Drug Discov Today       Date:  2011-05-20       Impact factor: 7.851

3.  High lipophilicity and high daily dose of oral medications are associated with significant risk for drug-induced liver injury.

Authors:  Minjun Chen; Jürgen Borlak; Weida Tong
Journal:  Hepatology       Date:  2013-05-27       Impact factor: 17.425

4.  Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).

Authors:  Zhichao Liu; Qiang Shi; Don Ding; Reagan Kelly; Hong Fang; Weida Tong
Journal:  PLoS Comput Biol       Date:  2011-12-15       Impact factor: 4.475

  4 in total
  3 in total

1.  Discovery of potential antifungal triazoles: design, synthesis, biological evaluation, and preliminary antifungal mechanism exploration.

Authors:  Yuan Zhang; Guri L V Damu; Sheng-Feng Cui; Jia-Li Mi; Vijai Kumar Reddy Tangadanchu; Cheng-He Zhou
Journal:  Medchemcomm       Date:  2017-06-15       Impact factor: 3.597

2.  A transcriptomics data-driven gene space accurately predicts liver cytopathology and drug-induced liver injury.

Authors:  Pekka Kohonen; Juuso A Parkkinen; Egon L Willighagen; Rebecca Ceder; Krister Wennerberg; Samuel Kaski; Roland C Grafström
Journal:  Nat Commun       Date:  2017-07-03       Impact factor: 14.919

3.  The eTRANSAFE Project on Translational Safety Assessment through Integrative Knowledge Management: Achievements and Perspectives.

Authors:  François Pognan; Thomas Steger-Hartmann; Carlos Díaz; Niklas Blomberg; Frank Bringezu; Katharine Briggs; Giulia Callegaro; Salvador Capella-Gutierrez; Emilio Centeno; Javier Corvi; Philip Drew; William C Drewe; José M Fernández; Laura I Furlong; Emre Guney; Jan A Kors; Miguel Angel Mayer; Manuel Pastor; Janet Piñero; Juan Manuel Ramírez-Anguita; Francesco Ronzano; Philip Rowell; Josep Saüch-Pitarch; Alfonso Valencia; Bob van de Water; Johan van der Lei; Erik van Mulligen; Ferran Sanz
Journal:  Pharmaceuticals (Basel)       Date:  2021-03-08
  3 in total

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