Literature DB >> 2714803

A gene homologous to plasminogen located on human chromosome 2q11-p11.

S L Frank1, I Klisak, R S Sparkes, A J Lusis.   

Abstract

A plasminogen probe encoding kringles 1-3 detects homologous loci on human chromosomes 6 and 2 by somatic cell hybrid analysis. Regional localization by in situ hybridization places the loci at 6q26-27 and 2p11-q11. Further analysis by varying washing stringencies of hybridization filters reveals a greater homology with the chromosome 6 locus than with the chromosome 2 locus. These results confirm localization of the plasminogen gene to human chromosome 6q26-27 and indicate that a homologous sequence of unknown identity resides on chromosome 2p11-q11.

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Year:  1989        PMID： 2714803     DOI： 10.1016/0888-7543(89)90356-x

Source DB:  PubMed          Journal:  Genomics        ISSN： 0888-7543            Impact factor:   5.736


  5 in total

Review 1.  Lipoprotein(a): its inheritance and molecular basis of its atherothrombotic role.

Authors:  A M Scanu
Journal:  Mol Cell Biochem       Date:  1992-08-18       Impact factor: 3.396

Review 2.  Comparative map for mice and humans.

Authors:  J H Nadeau; M T Davisson; D P Doolittle; P Grant; A L Hillyard; M R Kosowsky; T H Roderick
Journal:  Mamm Genome       Date:  1992       Impact factor: 2.957

3.  Characterization by yeast artificial chromosome cloning of the linked apolipoprotein(a) and plasminogen genes and identification of the apolipoprotein(a) 5' flanking region.

Authors:  N Malgaretti; F Acquati; P Magnaghi; L Bruno; M Pontoglio; M Rocchi; S Saccone; G Della Valle; M D'Urso; D LePaslier
Journal:  Proc Natl Acad Sci U S A       Date:  1992-12-01       Impact factor: 11.205

4.  Molecular basis of apolipoprotein (a) isoform size heterogeneity as revealed by pulsed-field gel electrophoresis.

Authors:  C Lackner; E Boerwinkle; C C Leffert; T Rahmig; H H Hobbs
Journal:  J Clin Invest       Date:  1991-06       Impact factor: 14.808

Review 5.  Comparative map for mice and humans.

Authors:  J H Nadeau; M T Davisson; D P Doolittle; P Grant; A L Hillyard; M Kosowsky; T H Roderick
Journal:  Mamm Genome       Date:  1991       Impact factor: 2.957
  5 in total

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