Literature DB >> 2714793

Assignment of the human intestinal Na+/glucose cotransporter gene (SGLT1) to the q11.2----qter region of chromosome 22.

M A Hediger1, M L Budarf, B S Emanuel, T K Mohandas, E M Wright.   

Abstract

The chromosomal location of the human intestinal Na+/glucose cotransporter gene (SGLT1) was determined using human cDNA and genomic probes for this transporter gene. Southern blot analysis of genomic DNA from 15 mouse-human somatic cell hybrids showed that the human gene for this transporter resides on chromosome 22. Analysis of hamster-human hybrids selectively retaining chromosome 22 or a portion of it allowed specific assignment of the locus to the q11.2----qter region of chromosome 22. A restriction fragment length polymorphism was identified with EcoRI.

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Year:  1989        PMID： 2714793     DOI： 10.1016/0888-7543(89)90333-9

Source DB:  PubMed          Journal:  Genomics        ISSN： 0888-7543            Impact factor:   5.736


  11 in total

Review 1.  Molecular genetics of the human Na+/glucose cotransporter.

Authors:  M A Hediger; E Turk; A M Pajor; E M Wright
Journal:  Klin Wochenschr       Date:  1989-09-01

Review 2.  Molecular genetics of intestinal glucose transport.

Authors:  E M Wright; E Turk; B Zabel; S Mundlos; J Dyer
Journal:  J Clin Invest       Date:  1991-11       Impact factor: 14.808

3.  Nephrocalcinosis in glucose-galactose malabsorption, association with renal tubular acidosis.

Authors:  Walid El-Naggar; J Williamson Balfe; Maha Barbar; Doris Taha
Journal:  Pediatr Nephrol       Date:  2005-07-12       Impact factor: 3.714

4.  Amino acid sequence and the cellular location of the Na(+)-dependent D-glucose symporters (SGLT1) in the ovine enterocyte and the parotid acinar cell.

Authors:  P S Tarpey; I S Wood; S P Shirazi-Beechey; R B Beechey
Journal:  Biochem J       Date:  1995-11-15       Impact factor: 3.857

Review 5.  Function and presumed molecular structure of Na(+)-D-glucose cotransport systems.

Authors:  H Koepsell; J Spangenberg
Journal:  J Membr Biol       Date:  1994-02       Impact factor: 1.843

6.  Regulation of glucose transporters in LLC-PK1 cells: effects of D-glucose and monosaccharides.

Authors:  T Ohta; K J Isselbacher; D B Rhoads
Journal:  Mol Cell Biol       Date:  1990-12       Impact factor: 4.272

7.  Cloning and chromosomal localization of a human kidney cDNA involved in cystine, dibasic, and neutral amino acid transport.

Authors:  W S Lee; R G Wells; R V Sabbag; T K Mohandas; M A Hediger
Journal:  J Clin Invest       Date:  1993-05       Impact factor: 14.808

8.  The human kidney low affinity Na+/glucose cotransporter SGLT2. Delineation of the major renal reabsorptive mechanism for D-glucose.

Authors:  Y Kanai; W S Lee; G You; D Brown; M A Hediger
Journal:  J Clin Invest       Date:  1994-01       Impact factor: 14.808

9.  Comparative mapping of the constitutional and tumor-associated 11;22 translocations.

Authors:  M Budarf; B Sellinger; C Griffin; B S Emanuel
Journal:  Am J Hum Genet       Date:  1989-07       Impact factor: 11.025

10.  Characterization of glucose transport by cultured rabbit kidney proximal convoluted and proximal straight tubule cells.

Authors:  Pedro L Del Valle; Anna Trifillis; Charles E Ruegg; Andrew S Kane
Journal:  In Vitro Cell Dev Biol Anim       Date:  2002-04       Impact factor: 2.416
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