Literature DB >> 27147713

Cefepime-Induced Neurotoxicity Despite Dose Adjustment for Renal Disease: A Brief Report and Review of the Literature.

Holly Lindsay1, Stephanie Gruner1, Julienne Brackett1.   

Abstract

Cefepime is increasingly used as empiric treatment for fever in the setting of neutropenia. We present a patient with acute-on-chronic renal disease who received cefepime at the appropriate dose for his glomerular filtration rate but developed cefepime-associated encephalopathy. Here, we review neurologic toxicities of cefepime and present suggestions for work-up and management.
© The Author 2016. Published by Oxford University Press on behalf of The Journal of the Pediatric Infectious Diseases Society. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Entities:  

Keywords:  cefepime; encephalopathy; leukemia; neurotoxicity; renal

Mesh：

Substances：

Year:  2017        PMID： 27147713     DOI： 10.1093/jpids/piw022

Source DB:  PubMed          Journal:  J Pediatric Infect Dis Soc        ISSN： 2048-7193            Impact factor:   3.164


  8 in total

1.  Cefepime Induced Neurotoxicity Following A Regimen Dose-Adjusted for Renal Function: Case Report and Review of the Literature.

Authors:  Michael L Behal; Jenni K Thomas; Melissa L Thompson Bastin; Breanne M Mefford
Journal:  Hosp Pharm       Date:  2021-09-16

2.  Approach to Cefepime-Induced Neurotoxicity in the Setting of Chronic Kidney Disease: A Case Report and Review of Literature.

Authors:  Ariel Ruiz de Villa; Kipson Charles; Raghav Bassi; Sanjae Spencer; Yvette Bazikian
Journal:  Cureus       Date:  2022-06-16

3.  Clinical characteristics and outcomes of antibiotic-associated encephalopathy in patients with end-stage kidney disease.

Authors:  Qingxiu Huang; Jianbo Li; Naya Huang; Xi Xia; Yagui Qiu; Zhong Zhong; Zhenchuan Lin; Xiaowen Huang; Dihua Zhang; Fengxian Huang
Journal:  Ren Fail       Date:  2022-12       Impact factor: 3.222

4.  Cefepime is Associated with Acute Encephalopathy in Critically Ill Patients: A Retrospective Case-Control Study.

Authors:  Tarun D Singh; John C O'Horo; Courtney N Day; Jay Mandrekar; Alejandro A Rabinstein
Journal:  Neurocrit Care       Date:  2020-12       Impact factor: 3.210

5.  Antimicrobial exposure and the risk of delirium in critically ill patients.

Authors:  Jessica J Grahl; Joanna L Stollings; Shayan Rakhit; Anna K Person; Li Wang; Jennifer L Thompson; Pratik P Pandharipande; E Wesley Ely; Mayur B Patel
Journal:  Crit Care       Date:  2018-12-12       Impact factor: 9.097

6.  Cefepime-Induced Encephalopathy With Seizures in a Pediatric Patient With End-Stage Renal Disease Rapidly Reversed by High-Efficiency Hemodialysis.

Authors:  Siddharth Shah; Stephanie Bland
Journal:  Cureus       Date:  2021-03-12

7.  Neurobehavioral Effects of Cephalosporins: Assessment of Locomotors Activity, Motor and Sensory Development in Zebrafish.

Authors:  Ying Han; Yangmin Zheng; Jingpu Zhang; Changqin Hu
Journal:  Front Pharmacol       Date:  2018-03-02       Impact factor: 5.810

Review 8.  Prolonged Cefepime-Induced Neurotoxicity in a Patient with End-Stage Renal Disease.

Authors:  Dorothy Dao Nguyen; Samuel Lai
Journal:  Am J Case Rep       Date:  2022-01-24
  8 in total

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