Literature DB >> 27147381

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Year:  2016        PMID: 27147381      PMCID: PMC4861090          DOI: 10.1136/bmjopen-2015-010210corr1

Source DB:  PubMed          Journal:  BMJ Open        ISSN: 2044-6055            Impact factor:   2.692


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Sharma M, Nazareth I, Petersen I. Trends in incidence, prevalence and prescribing in type 2 diabetes mellitus between 2000 and 2013 in primary care: a retrospective cohort study. BMJ Open 2016;6:e010210. The data in the original Table 2 showed proportional distribution by gender, social deprivation and age within the dataset rather that population prevalence. We have now replaced this information with estimates of prevalence and the updated Table 2 (see below). Table 2 now includes prevalence estimates by calendar year (as before) as well as prevalence estimates by gender, age and quintiles of Townsend deprivation for 2013 (the last year of our study period). Related changes have been made to the method, results and discussion section where relevant.
Table 2

Prevalence of type 2 diabetes mellitus per 100 individuals by calendar year and by socio-demographic factors for 2013 only

Prevalence of Type 2 Diabetes in 2013 by socio-demographic factors
Percentage Prevalence (95% CI)Adjusted PR (95% CI)*
Gender
Men5.91 (5.88 to 5.94)1
Woman5.11 (5.08 to 5.14)0.79 (0.79 to 0.80)
Age, years
0–90.03 (0.02 to 0.03)0.01 (0.01 to 0.01)
10–190.14 (0.13 to 0.15)0.03 (0.03 to 0.04)
20–290.6 (0.58 to 0.62)0.15 (0.15 to 0.16)
30–391.65 (1.62 to 1.68)0.42 (0.41 to 0.43)
40–493.70 (3.66 to 3.75)1
50–597.76 (7.69 to 7.82)2.16 (2.13 to 2.20)
60–6912.95 (12.85 to 13.04)3.73 (3.67 to 3.79)
70–7918.75 (18.61 to 18.88)5.48 (5.40 to 5.56)
80–8919.29 (19.11 to 19.46)5.69 (5.60 to 5.78)
90–9913.44 (13.14 to 13.75)4.07 (3.96 to 4.19)
Townsend Quintile
15.00 (4.95 to 5.04)1
25.52 (5.47 to 5.56)1.11 (1.10 to 1.13)
35.67 (5.63 to 5.72)1.31 (1.30 to 1.33)
45.94 (5.89 to 5.99)1.53 (1.51 to 1.54)
56.25 (6.19 to 6.31)1.75 (1.73 to 1.78)
Annual Prevalence of Type 2 Diabetes between 2000–2013
Year
20002.39 (2.37 to 2.41)1
20012.60 (2.58 to 2.62)1.10 (1.08 to 1.11)
20022.84 (2.83 to 2.86)1.20 (1.19 to 1.21)
20033.11 (3.09 to 3.13)1.32 (1.30 to 1.33)
20043.40 (3.38 to 3.42)1.44 (1.43 to 1.45)
20053.66 (3.64 to 3.67)1.55 (1.53 to 1.56)
20063.88 (3.86 to 3.90)1.64 (1.63 to 1.65)
20074.10 (4.08 to 4.12)1.73 (1.71 to 1.74)
20084.33 (4.32 to 4.35)1.82 (1.81 to 1.84)
20094.56 (4.54 to 4.58)1.91 (1.90 to 1.93)
20104.78 (4.76 to 4.80)2.01 (1.99 to 2.02)
20114.98 (4.96 to 5.00)2.08 (2.07 to 2.10)
20125.17 (5.15 to 5.19)2.16 (2.14 to 2.18)
20135.32 (5.30 to 5.34)2.21 (2.19 to 2.23)

*PR (prevalence ratios) mutually adjusted for other variables considered; gender, age band, Townsend quintile respectively.

**For figure displaying data above consult online supplementary appendix 2.

Prevalence of type 2 diabetes mellitus per 100 individuals by calendar year and by socio-demographic factors for 2013 only *PR (prevalence ratios) mutually adjusted for other variables considered; gender, age band, Townsend quintile respectively. **For figure displaying data above consult online supplementary appendix 2. (1) METHODS/Definition of main outcomes/Prevalence of T2DM should read: For our analysis on prevalence of T2DM by calendar year, we included as our numerator all individuals who had a record of T2DM on or before 1st January in the given year and as our denominator we included all patients registered to a general practice on or by 1st January in the given year. To estimate prevalence by age, gender and social deprivation, we identified numerators and denominators as described above. Given age changed with time we focused on data from 2013 and calculated age at 1st January 2013. Gender and social deprivation were considered as fixed variables. (2) METHODS/Statistical Analysis paragraph 2 should read: The crude prevalence of T2DM for each year was calculated by dividing the number of all individuals recorded as having T2DM on or before 1st January of that year by the total number of patients registered to a general practice on or by 1st January of that year. Multivariable Poisson regression analysis was used to estimate prevalence ratios of T2DM by year adjusted for age, gender and social deprivation as well as mutually adjusted ratios for age, gender and social deprivation for 2013. (3) RESULTS/Prevalence of T2DM from second sentence should read: Prevalence of T2DM in 2013 was 5.11 per 100 women and 5.91 per 100 men (Prevalence Ratio (PR) 0.79, 95% CI 0.79 to 0.80) (Table 2) and highest among individuals in the most deprived areas (Townsend quintile 5 vs Townsend quintile 1; (PR 1.75, 95% CI 1.73 to 1.78)). The prevalence increased with age. The highest prevalence for T2DM was seen in the 80–89 years age band: 19.29 per 100 individuals (95% CI 19.11 to 19.46). In comparison to individuals aged 40–49, the adjusted prevalence ratio for 80–89 years age band was 5.69, (95% CI 5.60 to 5.78) (Table 2). (4) DISCUSSION/Paragraph 1 from third sentence should read: Data from 2013 showed women were 21% less likely to have T2DM than men and those who were most socially deprived were 75% more likely to have T2DM, as compared to those least deprived. Individuals aged 80–89 years had the highest adjusted prevalence of T2DM, which was nearly six times higher than individuals aged 40–49 years.
  1 in total

1.  Trends in medication use in patients with type 2 diabetes mellitus: a long-term view of real-world treatment between 2000 and 2015.

Authors:  Victoria Higgins; James Piercy; Adam Roughley; Gary Milligan; Andrea Leith; James Siddall; Mike Benford
Journal:  Diabetes Metab Syndr Obes       Date:  2016-11-01       Impact factor: 3.168

  1 in total

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