BACKGROUND: Inguinal lymphadenectomy is essential for regional staging of malignant melanoma in the lower part of the body. The procedure is associated with a wide range of complication rates. The objective of this study was to systematically review the literature for papers describing complication rates following inguinal (ID) and ilioinguinal (I-ID) lymphadenectomies, and estimate the actual complication rates in patients with malignant melanoma. METHODS: The PubMed and EMBASE databases were searched for studies reporting complications following ID and I-ID for malignant melanomas. RESULTS: A total of 416 records were identified, of which 20 were deemed eligible for this study. The complication rates (with 95% confidence intervals) were found to be as follows: overall complications = 52% (44-60%); lymphorrea = 29% (0-71%); seroma = 23% (18-29%); infection = 21% (15-27%); wound breakdown =14% (8-21%); skin edge necrosis = 10% (6-15%); haematoma = 3% (1-5%); and lymphoedema = 33% (25-42%). CONCLUSION: Complication rates following ID and I-ID remain high, despite the many efforts to reduce these, with lymphorrea, seromas, and infections being the most prevalent complications.
BACKGROUND: Inguinal lymphadenectomy is essential for regional staging of malignant melanoma in the lower part of the body. The procedure is associated with a wide range of complication rates. The objective of this study was to systematically review the literature for papers describing complication rates following inguinal (ID) and ilioinguinal (I-ID) lymphadenectomies, and estimate the actual complication rates in patients with malignant melanoma. METHODS: The PubMed and EMBASE databases were searched for studies reporting complications following ID and I-ID for malignant melanomas. RESULTS: A total of 416 records were identified, of which 20 were deemed eligible for this study. The complication rates (with 95% confidence intervals) were found to be as follows: overall complications = 52% (44-60%); lymphorrea = 29% (0-71%); seroma = 23% (18-29%); infection = 21% (15-27%); wound breakdown =14% (8-21%); skin edge necrosis = 10% (6-15%); haematoma = 3% (1-5%); and lymphoedema = 33% (25-42%). CONCLUSION: Complication rates following ID and I-ID remain high, despite the many efforts to reduce these, with lymphorrea, seromas, and infections being the most prevalent complications.
Authors: Amanda J Stolarz; Mustafa Sarimollaoglu; John C Marecki; Terry W Fletcher; Ekaterina I Galanzha; Sung W Rhee; Vladimir P Zharov; V Suzanne Klimberg; Nancy J Rusch Journal: J Pharmacol Exp Ther Date: 2019-08-22 Impact factor: 4.030
Authors: Enrique Boldo; Araceli Mayol; Rafael Lozoya; Alba Coret; Diana Escribano; Carlos Fortea; Andres Muñoz; Juan Carlos Pastor; Guillermo Perez De Lucia Journal: Melanoma Manag Date: 2020-07-21
Authors: Peter Dall; Thomas Hildebrandt; Andreas du Bois; Eric Boetel; Janine Ahlfaenger; Matthias W Beckmann; Mareike Bommert Journal: Arch Gynecol Obstet Date: 2020-04-18 Impact factor: 2.344