Literature DB >> 27146631

Management and outcomes of anastomotic leaks after oesophagectomy.

B Dent1, S M Griffin1, R Jones1, S Wahed1, A Immanuel1, N Hayes1.   

Abstract

BACKGROUND: Leaks following oesophagectomy include true anastomotic leaks, leaks from the gastrotomy and gastric conduit necrosis. Historically, these complications were associated with high mortality rates. Recent improvements in outcome have been attributed to the wider use of oesophageal stents in patient management. This study examined outcomes of patients who developed a leak in a single high-volume institution that did not use stenting as a primary treatment modality.
METHODS: All patients undergoing an oesophagectomy between January 2009 and December 2013 were included. Patients were identified from a prospectively maintained database.
RESULTS: A total of 390 oesophagectomies were performed (median age 65 (range 32-81) years). In 96·7 per cent of patients this was a two-stage subtotal oesophagectomy. Overall in-hospital and 90-day mortality rates were both 2·1 per cent (8 patients). Some 31 patients (7·9 per cent) developed a leak (median age 64·5 (range 52-80) years), of whom 27 (87 per cent) were initially managed without surgery, whereas four (13 per cent) required immediate thoracotomy. The median length of stay for patients with a leak was 41·5 (range 15-159) days; none of these patients died.
CONCLUSION: Leaks can be managed with excellent outcomes without using oesophageal stents. The results do not support the widespread adoption of endoscopic stenting.
© 2016 BJS Society Ltd Published by John Wiley & Sons Ltd.

Entities:  

Mesh:

Substances:

Year:  2016        PMID: 27146631     DOI: 10.1002/bjs.10175

Source DB:  PubMed          Journal:  Br J Surg        ISSN: 0007-1323            Impact factor:   6.939


  16 in total

1.  Comparison of Outcomes with Semi-mechanical and Circular Stapled Intrathoracic Esophagogastric Anastomosis following Esophagectomy.

Authors:  Fady Yanni; Pritam Singh; Nilanjana Tewari; Simon L Parsons; James A Catton; John Duffy; Neil T Welch; Ravinder S Vohra
Journal:  World J Surg       Date:  2019-10       Impact factor: 3.352

2.  Significant decrease of mortality due to anastomotic leaks following esophageal resection: management makes the difference.

Authors:  Anja Schaible; Thorsten Brenner; Ulf Hinz; Thomas Schmidt; Markus Weigand; Peter Sauer; Markus W Büchler; Alexis Ulrich
Journal:  Langenbecks Arch Surg       Date:  2017-10-03       Impact factor: 3.445

3.  We Asked the Experts: "To Stent or Not to Stent… What is the Best Management of an Esophageal Leak or Benign Perforation?"

Authors:  Sarah K Thompson; David I Watson
Journal:  World J Surg       Date:  2020-04       Impact factor: 3.352

Review 4.  Critical Appraisal of the Impact of Oesophageal Stents in the Management of Oesophageal Anastomotic Leaks and Benign Oesophageal Perforations: An Updated Systematic Review.

Authors:  Sivesh K Kamarajah; James Bundred; Gary Spence; Andrew Kennedy; Bobby V M Dasari; Ewen A Griffiths
Journal:  World J Surg       Date:  2020-04       Impact factor: 3.352

5.  Thoracoscopy in prone position with two-lung ventilation compared to conventional thoracotomy during Ivor Lewis procedure: a multicenter case-control study.

Authors:  R Souche; M Nayeri; R Chati; E Huet; I Donici; J J Tuech; F Borie; M Prudhomme; S Jaber; J M Fabre
Journal:  Surg Endosc       Date:  2019-03-13       Impact factor: 4.584

6.  Is Prophylactic Cervical Drainage Effective in Patients Undergoing McKeown Esophagectomy Reconstructed Through the Retrosternal Route with Two-Field Lymphadenectomy?

Authors:  Daisuke Fujiwara; Masayuki Watanabe; Yasukazu Kanie; Suguru Maruyama; Kei Sakamoto; Akihiko Okamura; Jun Kanamori; Yu Imamura; Shinji Mine
Journal:  World J Surg       Date:  2022-04-20       Impact factor: 3.282

7.  Management of anastomotic leaks following esophagectomy: when to intervene?

Authors:  Joshua L Manghelli; DuyKhanh P Ceppa; Jason W Greenberg; David Blitzer; Adam Hicks; Karen M Rieger; Thomas J Birdas
Journal:  J Thorac Dis       Date:  2019-01       Impact factor: 2.895

8.  Endoscopic vacuum therapy versus stent treatment of esophageal anastomotic leaks (ESOLEAK): study protocol for a prospective randomized phase 2 trial.

Authors:  Michael Tachezy; Seung-Hun Chon; Isabel Rieck; Marcus Kantowski; Hildegard Christ; Karl Karstens; Florian Gebauer; Tobias Goeser; Thomas Rösch; Jakob R Izbicki; Christiane J Bruns
Journal:  Trials       Date:  2021-06-02       Impact factor: 2.279

9.  ASO Author Reflections: Anastomotic Leaks After Esophagectomy-No Impact on Long-Term Survival.

Authors:  Sivesh K Kamarajah; Alexander W Phillips
Journal:  Ann Surg Oncol       Date:  2020-01-23       Impact factor: 5.344

10.  Anastomotic Leak Does Not Impact on Long-Term Outcomes in Esophageal Cancer Patients.

Authors:  S K Kamarajah; M Navidi; S Wahed; A Immanuel; N Hayes; S M Griffin; A W Phillips
Journal:  Ann Surg Oncol       Date:  2020-01-23       Impact factor: 5.344

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.