Literature DB >> 27146403

Substitution as a Strategy to Improve Excipient Exposure in Neonates: One Piece of the Puzzle.

Karel Allegaert1,2,3, Isabel Spriet4,5.   

Abstract

Year:  2016        PMID： 27146403     DOI： 10.1007/s40272-016-0178-0

Source DB:  PubMed          Journal:  Paediatr Drugs        ISSN： 1174-5878            Impact factor:   3.022


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  12 in total

1.  The propylene glycol research project to illustrate the feasibility and difficulties to study toxicokinetics in neonates.

Authors:  Aida Kulo; Jan N de Hoon; Karel Allegaert
Journal:  Int J Pharm       Date:  2012-05-26       Impact factor: 5.875

2.  Propylene glycol produces excessive apoptosis in the developing mouse brain, alone and in combination with phenobarbital.

Authors:  Karen Lau; Brant S Swiney; Nick Reeves; Kevin K Noguchi; Nuri B Farber
Journal:  Pediatr Res       Date:  2012-01       Impact factor: 3.756

3.  The STEP database through the end-users eyes--USABILITY STUDY.

Authors:  Smita Salunke; Catherine Tuleu
Journal:  Int J Pharm       Date:  2015-06-24       Impact factor: 5.875

4.  The STEP (Safety and Toxicity of Excipients for Paediatrics) database: part 2 - the pilot version.

Authors:  Smita Salunke; Barbara Brandys; George Giacoia; Catherine Tuleu
Journal:  Int J Pharm       Date:  2013-09-23       Impact factor: 5.875

Review 5.  Neonatal drug therapy: The first frontier of therapeutics for children.

Authors:  K Allegaert; J van den Anker
Journal:  Clin Pharmacol Ther       Date:  2015-07-22       Impact factor: 6.875

6.  Acceptability of Uncoated Mini-Tablets in Neonates--A Randomized Controlled Trial.

Authors:  Viviane Klingmann; Annika Seitz; Thomas Meissner; Jörg Breitkreutz; Andreas Moeltner; Hans Martin Bosse
Journal:  J Pediatr       Date:  2015-08-07       Impact factor: 4.406

7.  Risk assessment of neonatal excipient exposure: lessons from food safety and other areas.

Authors:  M A Turner; J C Duncan; U Shah; T Metsvaht; H Varendi; G Nellis; I Lutsar; S Yakkundi; J C McElnay; H Pandya; H Mulla; P Vaconsin; T Storme; A Rieutord; A J Nunn
Journal:  Adv Drug Deliv Rev       Date:  2013-11-13       Impact factor: 15.470

8.  Product Substitution as a Way Forward in Avoiding Potentially Harmful Excipients in Neonates.

Authors:  Georgi Nellis; Tuuli Metsvaht; Heili Varendi; Jana Lass; Jennifer Duncan; Anthony J Nunn; Mark A Turner; Irja Lutsar
Journal:  Paediatr Drugs       Date:  2016-06       Impact factor: 3.022

Review 9.  Safety of Excipients in Pediatric Formulations-A Call for Toxicity Studies in Juvenile Animals?

Authors:  Georg Schmitt
Journal:  Children (Basel)       Date:  2015-05-15

10.  Essential medicines containing ethanol elevate blood acetaldehyde concentrations in neonates.

Authors:  H C Pandya; H Mulla; M Hubbard; R L Cordell; P S Monks; S Yakkundi; J C McElnay; A J Nunn; M A Turner
Journal:  Eur J Pediatr       Date:  2016-03-21       Impact factor: 3.183
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  1 in total

1.  Excipients in Neonatal Medicinal Products: Never Prescribed, Commonly Administered.

Authors:  Kristine Svinning Valeur; Helle Holst; Karel Allegaert
Journal:  Pharmaceut Med       Date:  2018-08-10
  1 in total

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