Literature DB >> 27146355

Triggering bilayer to inverted-hexagonal nanostructure formation by thiol-ene click chemistry on cationic lipids: consequences on gene transfection.

Damien Afonso1, Tony Le Gall2, Hélène Couthon-Gourvès1, Axelle Grélard3, Shipra Prakash3, Mathieu Berchel1, Nelly Kervarec1, Erick J Dufourc3, Tristan Montier4, Paul-Alain Jaffrès1.   

Abstract

The ramification of cationic amphiphiles on their unsaturated lipid chains is readily achieved by using the thiol-ene click reaction triggering the formation of an inverted hexagonal phase (HII). The new ramified cationic lipids exhibit different bio-activities (transfection, toxicity) including higher transfection efficacies on 16HBE 14o-cell lines.

Entities:  

Mesh：

Substances：

Year:  2016        PMID： 27146355     DOI： 10.1039/c6sm00609d

Source DB:  PubMed          Journal:  Soft Matter        ISSN： 1744-683X            Impact factor:   3.679


  5 in total

1.  Multimodal tumor-homing chitosan oligosaccharide-coated biocompatible palladium nanoparticles for photo-based imaging and therapy.

Authors:  Subramaniyan Bharathiraja; Nhat Quang Bui; Panchanathan Manivasagan; Madhappan Santha Moorthy; Sudip Mondal; Hansu Seo; Nguyen Thanh Phuoc; Thi Tuong Vy Phan; Hyehyun Kim; Kang Dae Lee; Junghwan Oh
Journal:  Sci Rep       Date:  2018-01-11       Impact factor: 4.379

2.  Lipid polymorphism in chloroplast thylakoid membranes - as revealed by 31P-NMR and time-resolved merocyanine fluorescence spectroscopy.

Authors:  Győző Garab; Bettina Ughy; Pieter de Waard; Parveen Akhtar; Uroš Javornik; Christos Kotakis; Primož Šket; Václav Karlický; Zuzana Materová; Vladimír Špunda; Janez Plavec; Herbert van Amerongen; László Vígh; Henk Van As; Petar H Lambrev
Journal:  Sci Rep       Date:  2017-10-17       Impact factor: 4.379

3.  Modulation of non-bilayer lipid phases and the structure and functions of thylakoid membranes: effects on the water-soluble enzyme violaxanthin de-epoxidase.

Authors:  Ondřej Dlouhý; Irena Kurasová; Václav Karlický; Uroš Javornik; Primož Šket; Nia Z Petrova; Sashka B Krumova; Janez Plavec; Bettina Ughy; Vladimír Špunda; Győző Garab
Journal:  Sci Rep       Date:  2020-07-20       Impact factor: 4.379

4.  Phosphonodithioester-Amine Coupling as a Key Reaction Step for the Design of Cationic Amphiphiles Used for Gene Delivery.

Authors:  Montassar Khalil; Alexis Hocquigny; Mathieu Berchel; Tristan Montier; Paul-Alain Jaffrès
Journal:  Molecules       Date:  2021-12-11       Impact factor: 4.411

5.  Aerosol-Mediated Non-Viral Lung Gene Therapy: The Potential of Aminoglycoside-Based Cationic Liposomes.

Authors:  Tony Le Gall; Mathieu Berchel; Lee Davies; Angélique Mottais; Rosy Ghanem; Alain Fautrel; Deborah Gill; Steve Hyde; Pierre Lehn; Jean-Marie Lehn; Loïc Lemiègre; Thierry Benvegnu; Paul-Alain Jaffrès; Bruno Pitard; Tristan Montier
Journal:  Pharmaceutics       Date:  2021-12-23       Impact factor: 6.321
  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.