Rie Asakura1,2, Nobuyuki Miyatake3, Kazumi Dokai Mochimasu3, Risa Kurato3, Susumu Kuwana4. 1. Takamatsu City Office, Takamatsu, 760-8571, Japan. asakura1127@med.kagawa-u.ac.jp. 2. Department of Hygiene, Faculty of Medicine, Kagawa University, Miki, 761-0793, Japan. asakura1127@med.kagawa-u.ac.jp. 3. Department of Hygiene, Faculty of Medicine, Kagawa University, Miki, 761-0793, Japan. 4. Kagawa Medical Office Attached To Takamatsu Municipal Hospital, Takamatsu, 761-1703, Japan.
Abstract
OBJECTIVE: The aim of this study was to compare health-related quality of life (HRQOL) between type 2 diabetic patients with and without locomotive syndrome, which is a risk for becoming bedridden because of deteriorating locomotive organs. SUBJECTS AND METHODS: A total of 135 patients with type 2 diabetes mellitus (69.2 ± 10.2 years) were enrolled in this cross-sectional study. HRQOL was evaluated by the Euro-QOL-5 (EQ-5D), and locomotive syndrome was evaluated by "loco-check," established the Japanese Orthopedic Association. Clinical data, such as anthropometric parameters, blood and urine examination results, blood pressure (BP), drug usage, and psychological distress, were analyzed. RESULTS: Average HbA1c in all patients was 7.2 ± 1.0 %, and 74 patients (54.8 %) were identified as having the locomotive syndrome. EQ-5D scores were significantly lower in type 2 diabetic patients with locomotive syndrome than in those without locomotive syndrome, even after adjusting for age, sex, body mass index (BMI), and HbA1c. By the multiple regression analysis, locomotive syndrome and age were identified as determinant factors of HRQOL in type 2 diabetic patients. CONCLUSION: In type 2 diabetic patients, lower HRQOL was a characteristic feature of subjects with locomotive syndrome, even after adjusting for confounding factors. Prevention or management of locomotive syndrome may be beneficial for improving HRQOL in type 2 diabetic patients.
OBJECTIVE: The aim of this study was to compare health-related quality of life (HRQOL) between type 2 diabeticpatients with and without locomotive syndrome, which is a risk for becoming bedridden because of deteriorating locomotive organs. SUBJECTS AND METHODS: A total of 135 patients with type 2 diabetes mellitus (69.2 ± 10.2 years) were enrolled in this cross-sectional study. HRQOL was evaluated by the Euro-QOL-5 (EQ-5D), and locomotive syndrome was evaluated by "loco-check," established the Japanese Orthopedic Association. Clinical data, such as anthropometric parameters, blood and urine examination results, blood pressure (BP), drug usage, and psychological distress, were analyzed. RESULTS: Average HbA1c in all patients was 7.2 ± 1.0 %, and 74 patients (54.8 %) were identified as having the locomotive syndrome. EQ-5D scores were significantly lower in type 2 diabeticpatients with locomotive syndrome than in those without locomotive syndrome, even after adjusting for age, sex, body mass index (BMI), and HbA1c. By the multiple regression analysis, locomotive syndrome and age were identified as determinant factors of HRQOL in type 2 diabeticpatients. CONCLUSION: In type 2 diabeticpatients, lower HRQOL was a characteristic feature of subjects with locomotive syndrome, even after adjusting for confounding factors. Prevention or management of locomotive syndrome may be beneficial for improving HRQOL in type 2 diabeticpatients.
Entities:
Keywords:
Health-related quality of life (HRQOL); Loco-check; Locomotive syndrome; Type 2 diabetes mellitus
Authors: Ronald C Kessler; Peggy R Barker; Lisa J Colpe; Joan F Epstein; Joseph C Gfroerer; Eva Hiripi; Mary J Howes; Sharon-Lise T Normand; Ronald W Manderscheid; Ellen E Walters; Alan M Zaslavsky Journal: Arch Gen Psychiatry Date: 2003-02
Authors: Valerie H Myers; Megan A McVay; Meghan M Brashear; Neil M Johannsen; Damon L Swift; Kimberly Kramer; Melissa Nauta Harris; William D Johnson; Conrad P Earnest; Timothy S Church Journal: Diabetes Care Date: 2013-02-12 Impact factor: 19.112