Literature DB >> 27145161

Nucleus Accumbens Deep Brain Stimulation for Alcohol Addiction - Safety and Clinical Long-term Results of a Pilot Trial.

U J Müller1, V Sturm2, J Voges3, H-J Heinze4, I Galazky4, L Büntjen3, M Heldmann4, T Frodl1, J Steiner1, B Bogerts1.   

Abstract

We report on the long-term clinical outcome (up to 8 years) of 5 patients who received deep brain stimulation (DBS) of the nucleus accumbens to treat their long-lasting and treatment-resistant alcohol addiction. All patients reported a complete absence of craving for alcohol; 2 patients remained abstinent for many years and 3 patients showed a marked reduction of alcohol consumption. No severe or long-standing side effects occurred. Therefore, DBS could be a promising, novel treatment option for severe alcohol addiction, but larger clinical trials are needed to further investigate the efficacy of DBS in addiction. © Georg Thieme Verlag KG Stuttgart · New York.

Entities:  

Mesh：

Year:  2016        PMID： 27145161     DOI： 10.1055/s-0042-104507

Source DB:  PubMed          Journal:  Pharmacopsychiatry        ISSN： 0176-3679            Impact factor:   5.788


  23 in total

Review 1.  Neuromodulation interventions for addictive disorders: challenges, promise, and roadmap for future research.

Authors:  Primavera A Spagnolo; David Goldman
Journal:  Brain       Date:  2017-05-01       Impact factor: 13.501

Review 2.  Neuroimaging reward, craving, learning, and cognitive control in substance use disorders: review and implications for treatment.

Authors:  Jody Tanabe; Michael Regner; Joseph Sakai; Diana Martinez; Joshua Gowin
Journal:  Br J Radiol       Date:  2019-05-14       Impact factor: 3.039

Review 3.  Reward Circuitry in Addiction.

Authors:  Sarah Cooper; A J Robison; Michelle S Mazei-Robison
Journal:  Neurotherapeutics       Date:  2017-07       Impact factor: 7.620

Review 4.  Outcomes of deep brain stimulation surgery for substance use disorder: a systematic review.

Authors:  Omron Hassan; Sheshanna Phan; Nicole Wiecks; Christian Joaquin; Vladimir Bondarenko
Journal:  Neurosurg Rev       Date:  2020-10-10       Impact factor: 3.042

Review 5.  Transcranial magnetic stimulation, deep brain stimulation, and other forms of neuromodulation for substance use disorders: Review of modalities and implications for treatment.

Authors:  James J Mahoney; Colleen A Hanlon; Patrick J Marshalek; Ali R Rezai; Lothar Krinke
Journal:  J Neurol Sci       Date:  2020-09-20       Impact factor: 3.181

Review 6.  The dopamine motive system: implications for drug and food addiction.

Authors:  Nora D Volkow; Roy A Wise; Ruben Baler
Journal:  Nat Rev Neurosci       Date:  2017-11-16       Impact factor: 34.870

Review 7.  New steps for treating alcohol use disorder.

Authors:  Erin J Campbell; Andrew J Lawrence; Christina J Perry
Journal:  Psychopharmacology (Berl)       Date:  2018-03-25       Impact factor: 4.530

8.  Deep brain stimulation of the nucleus accumbens shell attenuates cocaine withdrawal but increases cocaine self-administration, cocaine-induced locomotor activity, and GluR1/GluA1 in the central nucleus of the amygdala in male cocaine-dependent rats.

Authors:  Marsida Kallupi; Jenni Kononoff; Philippe A Melas; Johanna S Qvist; Giordano de Guglielmo; Eric R Kandel; Olivier George
Journal:  Brain Stimul       Date:  2021-11-03       Impact factor: 8.955

Review 9.  A review of brain stimulation methods to treat substance use disorders.

Authors:  Alexandria S Coles; Karolina Kozak; Tony P George
Journal:  Am J Addict       Date:  2018-02-19

Review 10.  Treatment for Substance Use Disorder With Co-Occurring Mental Illness.

Authors:  Muhammad N Iqbal; Charles J Levin; Frances R Levin
Journal:  Focus (Am Psychiatr Publ)       Date:  2019-04-10
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.